Acetamide

Acetamide

SCHEMBL11118916

CC(N)=O.COC(C)OC

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.50
ALOX15 P16050 1/20 0.50
BLM P54132 1/20 0.50
PMP22 Q01453 1/20 0.50
ALDH1A1 P00352 3/20 0.37
TSHR P16473 3/20 0.36
SLC1A3 P43003 1/20 0.35
SLC1A2 P43004 1/20 0.35
SLC1A1 P43005 1/20 0.35
TDP1 Q9NUW8 2/20 0.33
CA14 Q9ULX7 1/20 0.33
CHRM2 P08172 1/20 0.31
CHRM4 P08173 1/20 0.31
CHRM5 P08912 1/20 0.31
CHRM1 P11229 1/20 0.31
CHRM3 P20309 1/20 0.31
CYP2C9 P11712 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
CRBN Q96SW2 1/20 0.30
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetone SCHEMBL593191 0.87 LMNA (0.43) LMNAALDH1A1TSHRSLC1A3SLC1A2
Isobutyramide SCHEMBL355821 0.85 SLC1A3 (0.33) LMNAALOX15BLMPMP22TSHR
Acetic Acid SCHEMBL10711426 0.84 FFAR3 (0.47) LMNAALDH1A1TSHRSLC1A3SLC1A2
Propionamide SCHEMBL10434987 0.80 ALOX15 (0.36) LMNAALOX15BLMPMP22ALDH1A1
Bicarbonate SCHEMBL6258274 0.80 TP53 (0.39) ALDH1A1TSHRSLC1A3SLC1A2SLC1A1
Acrylamide SCHEMBL28449014 0.78 TSHR (0.55) LMNAALDH1A1TSHRSLC1A3SLC1A2
SCHEMBL510374 0.77
SCHEMBL349574 0.77 TSHR (0.33) ALDH1A1TSHRCHRM2CHRM4CHRM5
Alanine SCHEMBL5676881 0.77 SLC1A3 (0.48) ALDH1A1SLC1A3SLC1A2SLC1A1MAPT
Butanone SCHEMBL8748901 0.77 ALDH1A1 (0.56) LMNAALDH1A1TSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109320439-A Synthesis and separation method of N' - (4-alkylphenyl) -N, N-dimethylamidine 中国石油天然气股份有限公司 2019-02-12 CN disclosed
CN-104981469-B Antimicrobial 罗格斯新泽西州立大学 2018-03-20 CN disclosed
CN-103596929-B Pyrazole and pyrimidine tricycloalkenones as antioxidant inflammation modulators 里亚塔医药公司 2016-10-19 CN disclosed
CN-103443189-B Rubber composition and pneumatic tire 住友橡胶工业株式会社 2016-09-07 CN disclosed
CN-105722909-A Pneumatic tire 住友橡胶工业株式会社 2016-06-29 CN disclosed
CN-103987775-B Rubber composition and pneumatic tire 住友橡胶工业株式会社 2016-06-22 CN disclosed
CN-103003347-B Rubber combination and pneumatic tyre SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2016-03-09 CN disclosed
CN-102604177-B Rubber combination and pneumatic tyre SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2016-03-02 CN disclosed
CN-103732672-B Rubber combination and pneumatic tyre SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2016-01-20 CN disclosed
CN-103502345-B Rubber combination and pneumatic tyre SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2016-01-20 CN disclosed
CN-103492473-A Rubber composition and pneumatic tire SUMITOMO RUBBER IND 2014-01-01 CN disclosed
CN-103476852-A Rubber composition and pneumatic tire SUMITOMO RUBBER IND 2013-12-25 CN disclosed
CN-103450515-A Rubber compound used for studless tire and studless tire SUMITOMO RUBBER IND 2013-12-18 CN disclosed
CN-103443189-A Rubber composition and pneumatic tire SUMITOMO RUBBER IND 2013-12-11 CN disclosed
CN-103443191-A Rubber composition and pneumatic tire SUMITOMO RUBBER IND 2013-12-11 CN disclosed
CN-103003347-A Rubber composition and pneumatic tire SUMITOMO RUBBER IND 2013-03-27 CN disclosed
CN-102690309-A Floxuridine compound and preparation method and application thereof UNIV PLA 2ND MILITARY MEDICAL 2012-09-26 CN disclosed
CN-102604177-A Rubber composition and pneumatic tire SUMITOMO RUBBER IND 2012-07-25 CN disclosed
CN-102558263-A Doxifluridine derivative and preparation method and pharmaceutical application thereof SHANGHAI RUIGUANG BIOCHEMICAL SCI TECH DEV CO LTD 2012-07-11 CN disclosed
EP-0119571-A1 Rifamycins derivatives and preparation and pharmaceutical compositions thereof SPA SOCIETA' PRODOTTI ANTIBIOTICI S.p.A. (IT) 1984-09-26 EP disclosed