Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 7/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.37 |
| ▸ | ABAT | P80404 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | DBH | P09172 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11811379 | 0.83 | KMT2A (0.47) | CHEK1ALDH1A1POLBKMT2A | |
| SCHEMBL11807403 | 0.83 | KDM4E (0.46) | CHEK1ALDH1A1POLBNPSR1 | |
| SCHEMBL16365587 | 0.81 | CHEK1 (0.41) | CHEK1KMT2A | |
| SCHEMBL8204263 | 0.81 | ALDH1A1 (0.47) | CHEK1ALDH1A1CYP3A4TSHR | |
| SCHEMBL11814837 | 0.81 | GAA (0.44) | CHEK1POLBCYP3A4TSHRKMT2A | |
| SCHEMBL16367847 | 0.81 | LPL (0.44) | CHEK1TSHR | |
| SCHEMBL12157029 | 0.77 | CHEK1 (0.39) | CHEK1ALDH1A1POLBKMT2A | |
| Maleic Acid SCHEMBL27879743 | 0.74 | AMPD2 (0.43) | CHEK1ALDH1A1TSHRDRD4 | |
| SCHEMBL11119780 | 0.73 | PPARA (0.39) | CHEK1 | |
| SCHEMBL11811596 | 0.73 | SIGMAR1 (0.50) | CHEK1ALDH1A1CYP1A2TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0097616-A1 | Polyalkylpiperidine esters of sulfonic acids | CIBA-GEIGY AG (CH) | 1984-01-04 | — | — | EP | disclosed |