SCHEMBL11136707

SCHEMBL11136707

COC(=O)C(F)(F)C(F)(F)C(F)(F)C(=O)F

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
DGAT1 O75907 1/20 0.33
ALDH1A1 P00352 1/20 0.33
KCNN4 O15554 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10767125 0.95 DGAT1 (0.33) DGAT1ALDH1A1KCNN4
SCHEMBL11133771 0.93 THRB (0.34) DGAT1ALDH1A1
SCHEMBL10768181 0.93 THRB (0.34) DGAT1ALDH1A1
SCHEMBL517272 0.90 DGAT1 (0.39) DGAT1ALDH1A1KCNN4
SCHEMBL10763959 0.85 ALDH1A1 (0.39) DGAT1ALDH1A1KCNN4
SCHEMBL497763 0.85 DGAT1 (0.39) DGAT1ALDH1A1KCNN4
SCHEMBL672362 0.82 THRB (0.40) DGAT1ALDH1A1KCNN4
SCHEMBL11205420 0.82 THRB (0.40) DGAT1ALDH1A1KCNN4
SCHEMBL3082673 0.82 THRB (0.40) DGAT1ALDH1A1KCNN4
SCHEMBL517251 0.82 THRB (0.40) DGAT1ALDH1A1KCNN4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4401829-A Process for the preparation of perfluorinated carboxylic acid fluorides HOECHST AKTIENGESELLSCHAFT (DE) 1983-08-30 US disclosed
EP-0047949-B1 PROCESS FOR THE PREPARATION OF PERFLUORINATED ACID FLUORIDES HOECHST AKTIENGESELLSCHAFT (DE) 1983-07-27 EP disclosed
EP-0047949-A1 Process for the preparation of perfluorinated acid fluorides HOECHST AKTIENGESELLSCHAFT (DE) 1982-03-24 EP disclosed