Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11144993 | 0.85 | SOAT1 (0.48) | MAOBBACE1LMNAL3MBTL1 | |
| SCHEMBL16316790 | 0.81 | SMN1; SMN2 (0.65) | MAOBBACE1SMN1; SMN2TSHRPKM | |
| SCHEMBL13100208 | 0.80 | TRPV4 (0.51) | MAOBBACE1SMN1; SMN2KDM4ETSHR | |
| SCHEMBL28868246 | 0.80 | LMNA (0.47) | MAOBBACE1SMN1; SMN2TSHRLMNA | |
| SCHEMBL21761089 | 0.79 | SMN1; SMN2 (0.67) | SMN1; SMN2KDM4ETSHRGLAPKM | |
| SCHEMBL10957051 | 0.77 | ALDH1A1 (0.55) | SMN1; SMN2KDM4ETSHRGLAHSD17B10 | |
| SCHEMBL14520042 | 0.77 | MAOB (0.44) | MAOBBACE1SMN1; SMN2TSHRPKM | |
| SCHEMBL11127007 | 0.77 | LMNA (0.61) | MAOBLMNAHPGDHIF1AHSD17B10 | |
| SCHEMBL11143856 | 0.75 | MAOB (0.46) | MAOBBACE1SMN1; SMN2KDM4ELMNA | |
| SCHEMBL13370774 | 0.73 | HTR6 (0.58) | SMN1; SMN2KDM4EGLAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4404220-A | INSECTIDES | VELSICOL CHEMICAL CORPORATION (US) | 1983-09-13 | — | — | US | disclosed |
| US-4299772-A | INSECTICIDES | VELSICOL CHEMICAL CORPORATION (US) | 1981-11-10 | — | — | US | disclosed |