Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | WDR5 | P61964 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.38 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14520037 | 0.81 | KMT2A (0.57) | SMN1; SMN2L3MBTL1ALDH1A1GAAPOLB | |
| SCHEMBL14519874 | 0.81 | L3MBTL1 (0.60) | NPSR1SMN1; SMN2L3MBTL1ALDH1A1GAA | |
| SCHEMBL16316790 | 0.80 | SMN1; SMN2 (0.65) | MAOBSMN1; SMN2PKMBACE1L3MBTL1 | |
| SCHEMBL14519921 | 0.79 | SMN1; SMN2 (0.56) | SMN1; SMN2PKMALDH1A1WDR5GAA | |
| SCHEMBL14519923 | 0.79 | ALDH1A1 (0.55) | NPSR1SMN1; SMN2L3MBTL1ALDH1A1WDR5 | |
| SCHEMBL13100208 | 0.79 | TRPV4 (0.51) | MAOBSMN1; SMN2PKMBACE1L3MBTL1 | |
| SCHEMBL28868246 | 0.79 | LMNA (0.47) | MAOBSMN1; SMN2PKMBACE1L3MBTL1 | |
| SCHEMBL10959144 | 0.78 | ALDH1A1 (0.54) | NPSR1SMN1; SMN2L3MBTL1ALDH1A1WDR5 | |
| SCHEMBL11140481 | 0.77 | MAOB (0.46) | MAOBSMN1; SMN2PKMBACE1L3MBTL1 | |
| SCHEMBL13588814 | 0.74 | HTR6 (0.56) | PKML3MBTL1ALDH1A1POLBMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070078146-A1 | Antiinflamamtory agents; antiarthritic agents; inflammatory bowel disorders; multiple sclerosis; asthma | PHARMACIA CORPORATION | 2007-04-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070078146-A1 | Antiinflamamtory agents; antiarthritic agents; inflammatory bowel disorders; multiple sclerosis; asthma | MAPK1, MAPK3, MAPK4 | MAOB 3149/4885NPSR1 3274/4885SMN1; SMN2 2049/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.