SCHEMBL1114138

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL27825969	0.89	KCNH2 (0.57)	DRD2HRH1HTR1AHTR2ADRD3
	SCHEMBL1114455	0.81	DRD2 (0.51)	DRD2HTR1AHTR2ADRD3SLC6A2
	Hydrochloric Acid SCHEMBL27805479	0.80	KCNH2 (0.56)	DRD2HRH1HTR1AHTR2ASIGMAR1
	SCHEMBL1114442	0.77	LMNA (0.64)	DRD2HTR1AHTR2ADRD3SLC6A2
	SCHEMBL11278328	0.73	HRH1 (0.58)	DRD2HRH1HTR1AHTR2ADRD3
	SCHEMBL10865799	0.72	DRD2 (0.64)	DRD2HRH1HTR1AHTR2ADRD3
	SCHEMBL5178875	0.72	KCNH2 (0.57)	DRD2HRH1HTR1AHTR2ADRD3
	SCHEMBL27805478	0.72	KCNH2 (0.57)	DRD2HTR1AHTR2ADRD3ALDH1A1
	SCHEMBL1114848	0.72	HTR1A (0.66)	DRD2HTR1AHTR2ADRD3SLC6A2
	Hydrochloric Acid SCHEMBL1114721	0.71	HTR1A (0.65)	DRD2HTR1AHTR2ADRD3SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.