Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 6/20 | 0.52 |
| ▸ | DRD3 | P35462 | 5/20 | 0.52 |
| ▸ | DRD4 | P21917 | 4/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 2/20 | 0.46 |
| ▸ | HTR2A | P28223 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1114454 | 0.89 | ALDH1A1 (0.58) | DRD2DRD3DRD4HTR1AHTR2A | |
| SCHEMBL1114549 | 0.85 | DRD2 (0.52) | DRD2DRD3DRD4HTR1AHTR2A | |
| SCHEMBL1114430 | 0.78 | DRD2 (0.60) | DRD2DRD3DRD4HTR1AHTR2A | |
| SCHEMBL1114544 | 0.78 | LMNA (0.64) | DRD2DRD3DRD4HTR2AKDM4E | |
| SCHEMBL3611072 | 0.75 | DRD2 (0.58) | DRD2DRD3DRD4CYP1A2CYP2D6 | |
| SCHEMBL3618095 | 0.75 | DRD2 (0.86) | DRD2DRD3DRD4CYP1A2CYP2D6 | |
| SCHEMBL1114958 | 0.74 | DRD2 (0.51) | DRD2DRD3DRD4HTR1AHTR2A | |
| SCHEMBL1114814 | 0.74 | HTR1A (0.66) | DRD2DRD3DRD4HTR1AHTR2A | |
| SCHEMBL1780938 | 0.72 | DRD2 (0.57) | DRD2DRD3DRD4HTR1AHTR2A | |
| SCHEMBL1114351 | 0.71 | LMNA (0.63) | DRD2DRD3DRD4HTR1AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2279179-A2 | PHENYL PIPERAZINE COMPOUNDS, PHARMACEUTICAL COMPOSITION INCLUDING THE SAME, AND USE THEREOF | SK Holdings Co., Ltd. (KR) | 2011-02-02 | — | — | EP | claimed |
| WO-2009145591-A2 | PHENYL PIPERAZINE COMPOUNDS, PHARMACEUTICAL COMPOSITION INCLUDING THE SAME, AND USE THEREOF | SK HOLDINGS CO., LTD. (KR) | 2009-12-03 | — | — | WO | claimed |
| EP-2279179-A2 | PHENYL PIPERAZINE COMPOUNDS, PHARMACEUTICAL COMPOSITION INCLUDING THE SAME, AND USE THEREOF | SK Holdings Co., Ltd. (KR) | 2011-02-02 | — | — | EP | disclosed |
| WO-2009145591-A2 | PHENYL PIPERAZINE COMPOUNDS, PHARMACEUTICAL COMPOSITION INCLUDING THE SAME, AND USE THEREOF | SK HOLDINGS CO., LTD. (KR) | 2009-12-03 | — | — | WO | disclosed |