Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | FDPS | P14324 | 10/20 | 0.45 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.45 |
| ▸ | CES2 | O00748 | 1/20 | 0.45 |
| ▸ | GGPS1 | O95749 | 6/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8648600 | 1.00 | ALDH1A1 (0.48) | ALDH1A1TSHRFDPSSMPD1CES2 | |
| SCHEMBL1410547 | 1.00 | ALDH1A1 (0.48) | ALDH1A1TSHRFDPSSMPD1CES2 | |
| SCHEMBL3267268 | 1.00 | ALDH1A1 (0.48) | ALDH1A1TSHRFDPSSMPD1CES2 | |
| SCHEMBL25303536 | 1.00 | ALDH1A1 (0.48) | ALDH1A1TSHRFDPSSMPD1CES2 | |
| SCHEMBL10830500 | 1.00 | ALDH1A1 (0.48) | ALDH1A1TSHRFDPSSMPD1CES2 | |
| SCHEMBL25078902 | 1.00 | ALDH1A1 (0.48) | ALDH1A1TSHRFDPSSMPD1CES2 | |
| SCHEMBL6496847 | 1.00 | ALDH1A1 (0.48) | ALDH1A1TSHRFDPSSMPD1CES2 | |
| SCHEMBL1410499 | 0.98 | ALDH1A1 (0.44) | ALDH1A1TSHRFDPSSMPD1CES2 | |
| SCHEMBL1410419 | 0.91 | ALDH1A1 (0.44) | ALDH1A1TSHRFDPSSMPD1CES2 | |
| SCHEMBL11286145 | 0.84 | ACLY (0.42) | ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210220328-A1 | PYRROLE DERIVATIVES AS ACC INHIBITORS | ALMIRALL SA (ES) | 2021-07-22 | — | — | US | disclosed |
| CN-111886230-A | Pyrrole derivatives as ACC inhibitors | 阿尔米雷尔有限公司 | 2020-11-03 | — | — | CN | disclosed |
| EP-3724182-A1 | PYRROLE DERIVATIVES AS ACC INHIBITORS | Almirall S.A. (ES) | 2020-10-21 | — | — | EP | disclosed |
| WO-2019115405-A1 | PYRROLE DERIVATIVES AS ACC INHIBITORS | ALMIRALL, S.A. (ES) | 2019-06-20 | — | — | WO | disclosed |
| US-20140336227-A1 | 3-AMINO LACTAMS AS ANTI-INFLAMMATORY AGENTS | CAMBRIDGE ENTERPRISE LIMITED (GB) | 2014-11-13 | — | — | US | disclosed |
| EP-1896012-B1 | Anti-inflammatory agents | CAMBRIDGE ENTPR LTD (GB) | 2014-09-24 | — | — | EP | disclosed |
| CN-103830230-A | Anti-inflammatory agents | CAMBRIDGE ENTPR LTD | 2014-06-04 | — | — | CN | disclosed |
| CN-101227901-B | Anti-inflammatory agents | CAMBRIDGE ENTPR LTD | 2014-03-05 | — | — | CN | disclosed |
| CN-103393691-A | Anti-inflammatory agents | UNIV CAMBRIDGE TECH | 2013-11-20 | — | — | CN | disclosed |
| EP-1691814-B9 | ANTI-INFLAMMATORY AGENTS | CAMBRIDGE ENTPR LTD (GB) | 2013-02-20 | — | — | EP | disclosed |
| US-20030069204-A1 | Strain of streptomyces | SANKYO COMPANY LIMITED (JP) | 2003-04-10 | — | — | US | disclosed |
| US-6472384-B1 | Antimicrobial compounds | SANKYO COMPANY, LIMITED (JP) | 2002-10-29 | — | — | US | disclosed |
| EP-1095947-A1 | NOVEL ANTIBACTERIAL COMPOUNDS | Sankyo Company Limited (JP) | 2001-05-02 | — | — | EP | disclosed |
| EP-0546177-B1 | BENZOPYRAN DERIVATIVE, PRODUCTION THEREOF, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | TEIJIN LTD (JP) | 1998-01-07 | — | — | EP | disclosed |
| US-5574061-A | ANTILIPEMIC AGENT, ANTIATHEROSCLEROSIS, ACAT INHIBITOR | TEIJIN LIMITED (JP) | 1996-11-12 | — | — | US | disclosed |
| EP-0546177-A1 | BENZOPYRAN DERIVATIVE, PRODUCTION THEREOF, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | TEIJIN LIMITED (JP) | 1993-06-16 | — | — | EP | disclosed |
| EP-0297610-B1 | N-[(2,6-disubstituted)phenyl]-urea and carbamate inhibitors of acyl-CoA:cholesterol acyl-transferase | WARNER-LAMBERT COMPANY (US) | 1991-03-13 | — | — | EP | disclosed |
| US-4961867-A | Process for preventing corrosion of metals by contacting them with compositions prepared from amino substituted pyrazines and carboxylic acids carboxylic acid anhydrides, carboxylic acid, esters or carboxylic acid halides | THE DOW CHEMICAL COMPANY (US) | 1990-10-09 | — | — | US | disclosed |
| US-4861884-A | OIL WELL CORROSION INHIBITOR | THE DOW CHEMICAL COMPANY (US) | 1989-08-29 | — | — | US | disclosed |
| EP-0297610-A1 | N-[(2,6-disubstituted)phenyl]-urea and carbamate inhibitors of acyl-CoA:cholesterol acyl-transferase | WARNER-LAMBERT COMPANY (US) | 1989-01-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140336227-A1 | 3-AMINO LACTAMS AS ANTI-INFLAMMATORY AGENTS | IL1B, NFKBIA, IL1A | ALDH1A1 3956/4885TSHR 4364/4885FDPS 2561/4885 |
| US-20030069204-A1 | Strain of streptomyces | O60361, CYP8B1, MRPS34 | ALDH1A1 858/4885TSHR 3757/4885FDPS 415/4885 |
| US-20210220328-A1 | PYRROLE DERIVATIVES AS ACC INHIBITORS | ACACA, ACACB, PCCA | ALDH1A1 129/4885TSHR 4181/4885FDPS 136/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.