Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 6/20 | 0.55 |
| ▸ | ALOX12 | P18054 | 6/20 | 0.55 |
| ▸ | PIK3CA | P42336 | 5/20 | 0.55 |
| ▸ | XDH | P47989 | 1/20 | 0.54 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.54 |
| ▸ | ATP1A1 | P05023 | 3/20 | 0.51 |
| ▸ | ATP1B1 | P05026 | 3/20 | 0.51 |
| ▸ | ATP1A3 | P13637 | 3/20 | 0.51 |
| ▸ | ATP1B2 | P14415 | 3/20 | 0.51 |
| ▸ | ATP1A2 | P50993 | 3/20 | 0.51 |
| ▸ | ATP1B3 | P54709 | 3/20 | 0.51 |
| ▸ | FXYD2 | P54710 | 3/20 | 0.51 |
| ▸ | ATP1A4 | Q13733 | 3/20 | 0.51 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.51 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10994834 | 0.85 | ALOX15 (0.59) | ALOX15ALOX12PIK3CAXDHPFKFB3 | |
| SCHEMBL1306154 | 0.72 | PTPN1 (0.56) | ALOX15ALOX12PIK3CAXDHPFKFB3 | |
| SCHEMBL29951632 | 0.72 | PTPN1 (0.56) | ALOX15ALOX12PIK3CAXDHPFKFB3 | |
| SCHEMBL11370039 | 0.71 | KDM4E (0.56) | XDHKDM4EGAAMEN1MAPT | |
| SCHEMBL234354 | 0.71 | ALOX15 (0.75) | ALOX15ALOX12PIK3CAXDHPFKFB3 | |
| SCHEMBL11149977 | 0.71 | MAPT (0.62) | ALOX15KDM4EGAARECQLMEN1 | |
| SCHEMBL8315659 | 0.70 | ALOX12 (0.50) | ALOX15ALOX12XDHACE | |
| SCHEMBL28705298 | 0.70 | ALOX15 (0.73) | ALOX15ALOX12PIK3CAXDHPFKFB3 | |
| SCHEMBL30533224 | 0.70 | XDH (1.00) | ALOX15ALOX12PIK3CAXDHPFKFB3 | |
| SCHEMBL10562974 | 0.70 | ALOX15 (1.00) | ALOX15ALOX12PIK3CAXDHPFKFB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4415567-A | A 7B-CHROMONE-3-CARBOXAMIDO-2-/4-HYDROXY PHENYL/ACETAMIDO-2-CEPHEM DERIVATIVE | EISAI CO., LTD. (JP) | 1983-11-15 | — | — | US | disclosed |
| US-4344944-A | 7-α-methoxycephalosporin derivatives, and antibacterial drugs onctaining the same | EISAI CO., LTD. (JP) | 1982-08-17 | — | — | US | disclosed |
| US-4285941-A | ANTIBIOTICS | EISAI CO., LTD. (JP) | 1981-08-25 | — | — | US | disclosed |
| US-4285940-A | ANTIBIOTICS | EISAI CO., LTD. (JP) | 1981-08-25 | — | — | US | disclosed |
| US-4285939-A | ANTIBIOTICS | EISAI CO., LTD. (JP) | 1981-08-25 | — | — | US | disclosed |