SCHEMBL3576573

SCHEMBL3576573

COC(=O)c1cc(-c2ccccc2)c(C(=O)OC)c(C(=O)OC)c1C(=O)OC

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 7/20 0.58
KMT2A Q03164 7/20 0.58
MAPT P10636 7/20 0.58
ALDH1A1 P00352 5/20 0.58
TDP1 Q9NUW8 3/20 0.58
RECQL P46063 2/20 0.58
GABRA1 P14867 4/20 0.55
GABRG2 P18507 4/20 0.55
GABRB3 P28472 4/20 0.55
GABRA3 P34903 4/20 0.55
HTT P42858 1/20 0.53
HPGD P15428 3/20 0.51
LMNA P02545 3/20 0.51
PRKCZ Q05513 1/20 0.51
PPARG P37231 2/20 0.51
NCOR2 Q9Y618 2/20 0.51
NPSR1 Q6W5P4 1/20 0.51
GPR55 Q9Y2T6 1/20 0.51
KDM4E B2RXH2 3/20 0.50
GABRA5 P31644 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10425361 0.87 HTT (0.50) MEN1KMT2AMAPTALDH1A1TDP1
SCHEMBL29042677 0.85 GABRA1 (0.54) MEN1KMT2AMAPTALDH1A1TDP1
SCHEMBL29045583 0.85 MEN1 (0.53) MEN1KMT2AMAPTALDH1A1TDP1
SCHEMBL11152302 0.85 HTT (0.54) MEN1KMT2AMAPTALDH1A1TDP1
SCHEMBL12121707 0.84 GABRA1 (0.62) MEN1KMT2AMAPTALDH1A1TDP1
SCHEMBL15674611 0.84 HTT (0.50) MEN1KMT2AMAPTALDH1A1TDP1
SCHEMBL13228930 0.82 HTT (0.62) MEN1KMT2AMAPTALDH1A1TDP1
SCHEMBL8900121 0.80 ALDH1A1 (0.52) MEN1KMT2AMAPTALDH1A1TDP1
SCHEMBL27516914 0.79 ALDH1A1 (0.58) MEN1KMT2AMAPTALDH1A1TDP1
SCHEMBL9150609 0.79 HTT (0.55) MEN1KMT2AMAPTALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-61249977-A None JP disclosed
JP-60089444-A None JP disclosed
US-9469621-B2 Method for producing multisubstituted biphenyl compound and solid catalyst to be used therein KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2016-10-18 US disclosed
US-20150274689-A1 METHOD FOR PRODUCING MULTISUBSTITUTED BIPHENYL COMPOUND AND SOLID CATALYST TO BE USED THEREIN UBE CORPORATION (JP) 2015-10-01 US disclosed
CN-102329290-B Modified biphenyl type dianhydride intermediate containing cyano side chain and synthesis method and application thereof UNIV SICHUAN 2014-04-02 CN disclosed
US-8492565-B2 Biphenyltetracarboxylic acid dianhydride and process for producing the same, and polyimide formed from the same and process for producing the same MITSUBISHI CHEMICAL CORPORATION (JP) 2013-07-23 US disclosed
US-20130178597-A1 POLYIMIDE PRECURSOR, POLYIMIDE, AND MATERIALS TO BE USED IN PRODUCING SAME UBE INDUSTRIES, LTD. (JP) 2013-07-11 US disclosed
EP-2597111-A1 POLYIMIDE PRECURSOR, POLYIMIDE, AND MATERIALS TO BE USED IN PRODUCING SAME Ube Industries, Ltd. (JP) 2013-05-29 EP disclosed
US-20130012682-A1 BIPHENYLTETRACARBOXYLIC ACID DIANHYDRIDE AND PROCESS FOR PRODUCING THE SAME, AND POLYIMIDE FORMED FROM THE SAME AND PROCESS FOR PRODUCING THE SAME MITSUBISHI CHEMICAL CORPORATION (JP) 2013-01-10 US disclosed
US-8299273-B2 Biphenyltetracarboxylic acid dianhydride and process for producing the same, and polyimide formed from the same and process for producing the same MITSUBISHI CHEMICAL CORPORATION (JP) 2012-10-30 US disclosed
EP-0556806-B1 Process for producing biphenyltetracarboxylic dianhydride MITSUBISHI CHEM CORP (JP) 1996-05-29 EP disclosed
EP-0421046-B1 Process for producing highly pure 3,3',4,4' - biphenyltetra- carboxylic acid or dianhydride thereof HITACHI LTD (JP) 1995-06-14 EP disclosed
US-5258530-A Process for producing biphenyltetracarboxylic dianhydride MITSUBISHI KASEI CORPORATION (JP) 1993-11-02 US disclosed
EP-0556806-A1 Process for producing biphenyltetracarboxylic dianhydride Mitsubishi Chemical Corporation (JP) 1993-08-25 EP disclosed
US-4895596-A Method of recovering palladium catalyst UBE INDUSTRIES, LTD. (JP) 1990-01-23 US disclosed
JP-S61249977-A PRODUCTION OF BIPHENYLTETRACARBOXYLIC ACID DIANHYDRIDE OF HIGH PURITY MITSUBISHI CHEM IND LTD 1986-11-07 JP disclosed
WO-1986001200-A1 PROCESS FOR PREPARAING TETRAMETHYL BIPHENYLTETRACARBOXYLATE MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) 1986-02-27 WO disclosed
JP-S6089444-A PRODUCTION OF BIPHENYLTETRACARBOXYLIC ACID MITSUBISHI CHEM IND LTD 1985-05-20 JP disclosed
US-4294976-A DEHYDROGENATIVE DIMERIZATION IN THE PRESENCE OF OXALIC ACID AND A PALLADIUM CATALYST UBE INDUSTRIES, LTD. (JP) 1981-10-13 US disclosed
US-3940426-A CRYSTALLIZATION OF ISOMERS UBE INDUSTRIES, LTD. (JA) 1976-02-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130012682-A1 BIPHENYLTETRACARBOXYLIC ACID DIANHYDRIDE AND PROCESS FOR PRODUCING THE SAME, AND POLYIMIDE FORMED FROM THE SAME AND PROCESS FOR PRODUCING THE SAME PCCA, DDT, HPD MEN1 4231/4885KMT2A 345/4885MAPT 1474/4885
US-20150274689-A1 METHOD FOR PRODUCING MULTISUBSTITUTED BIPHENYL COMPOUND AND SOLID CATALYST TO BE USED THEREIN DDT, CYP1A1, CYP1B1 MEN1 3168/4885KMT2A 295/4885MAPT 3591/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.