Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | APAF1 | O14727 | 1/20 | 0.36 |
| ▸ | PLK4 | O00444 | 1/20 | 0.35 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15516935 | 0.76 | MAPK14 (0.42) | MEN1KMT2APLK4HTTALDH1A1 | |
| SCHEMBL2129184 | 0.74 | HSD17B10 (0.46) | PLK4CXCL12HTTALDH1A1MAPT | |
| SCHEMBL18154713 | 0.72 | ALOX5AP (0.43) | PLK4CXCL12HTTSMN1; SMN2HPGD | |
| SCHEMBL31721266 | 0.72 | NUDT1 (0.49) | MEN1KMT2AAPAF1ALDH1A1RAB9A | |
| SCHEMBL3693314 | 0.70 | PLK4 (0.39) | KMT2APLK4CXCL12HTTALDH1A1 | |
| SCHEMBL8423836 | 0.68 | RAB9A (0.41) | MEN1KMT2AAPAF1ALDH1A1SMN1; SMN2 | |
| SCHEMBL9121662 | 0.67 | HTT (0.59) | MEN1KMT2APLK4HTTGAA | |
| SCHEMBL21609746 | 0.66 | POLB (0.33) | MEN1KMT2AAPAF1GAAALDH1A1 | |
| SCHEMBL4272019 | 0.65 | ALDH1A1 (0.47) | MEN1KMT2AAPAF1PLK4HTT | |
| SCHEMBL9384543 | 0.64 | KDM4E (0.50) | MEN1KMT2AAPAF1HTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0008192-B1 | BIS(PYRIMIDYLOXY)-, BIS(PYRIMIDYLTHIO)-, AND PYRIMIDYLOXY-PYRIMIDYLTHIO-BENZENE DERIVATIVES AND THEIR USE AS HERBICIDES, AND PROCESSES OF PREPARING THEM | ICI AUSTRALIA LIMITED (AU) | 1983-10-12 | — | — | EP | disclosed |
| EP-0008192-B1 | BIS(PYRIMIDYLOXY)-, BIS(PYRIMIDYLTHIO)-, AND PYRIMIDYLOXY-PYRIMIDYLTHIO-BENZENE DERIVATIVES AND THEIR USE AS HERBICIDES, AND PROCESSES OF PREPARING THEM | ICI AUSTRALIA LIMITED (AU) | 1983-10-12 | — | — | EP | disclosed |
| EP-0008192-A1 | Bis(pyrimidyloxy)-, bis(pyrimidylthio)-, and pyrimidyloxy-pyrimidylthio-benzene derivatives and their use as herbicides, and processes of preparing them | ICI AUSTRALIA LIMITED (AU) | 1980-02-20 | — | — | EP | disclosed |