Allylamine

Allylamine

SCHEMBL1115529

C=CCN.C=CCN.O

nearest known ligand 0.00

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Known targets — ChEMBL curated mechanism

ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO

The experimentally established mechanism targets of Allylamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Allylamine SCHEMBL8858077 1.00 ALDH1A1 (0.90)
Allylamine SCHEMBL8858079 1.00 ALDH1A1 (0.90)
Allylamine SCHEMBL169953 1.00
Allylamine SCHEMBL28169112 0.95
Allylamine SCHEMBL28859167 0.95
Allylamine SCHEMBL27403991 0.95
Allylamine SCHEMBL6032547 0.95
Allylamine SCHEMBL15197 0.95
Allylamine SCHEMBL11373125 0.90
Allylamine SCHEMBL5891273 0.90

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106076190-A Shuangzi alkyl ether amine amber sulfonate surfactant and preparation method thereof 北京化艺科贸有限公司 2016-11-09 CN claimed
CN-1860364-A Fluorescent labelled ligands UNIV NOTTINGHAM (GB) 2006-11-08 CN claimed
US-12037537-B2 Method of and a composition for controlling gas hydrate blockage through the addition of a synergistically acting blend with alkoxylates of fatty alcohols, fatty amines and fatty acids CLARIANT INTERNATIONAL LTD (CH) 2024-07-16 US disclosed
US-11898091-B2 Synergistic blends of anti-agglomerant gas hydrate inhibitors with quaternary benzyl ammonium compounds CLARIANT INTERNATIONAL LTD (CH) 2024-02-13 US disclosed
US-11572499-B2 Method of and a composition for controlling gas hydrate blockage through the addition of a synergistically acting blend with a quaternary benzyl ammonium compound CLARIANT INTERNATIONAL LTD (CH) 2023-02-07 US disclosed
US-11549050-B2 Amorphous dithiazine dissolution formulation and method for using the same CLARIANT INTERNATIONAL LTD. (CH) 2023-01-10 US disclosed
EP-4073196-A1 A METHOD OF AND A COMPOSITION FOR CONTROLLING GAS HYDRATE BLOCKAGE THROUGH THE ADDITION OF A SYNERGISTICALLY ACTING BLEND WITH A QUATERNARY ALKYL AMMONIUM COMPOUND Clariant International Ltd (CH) 2022-10-19 EP disclosed
EP-4073198-A1 A METHOD OF AND A COMPOSITION FOR CONTROLLING GAS HYDRATE BLOCKAGE THROUGH THE ADDITION OF A SYNERGISTICALLY ACTING BLEND WITH ALKOXYLATES OF FATTY ALCOHOLS, FATTY AMINES OR FATTY ACIDS Clariant International Ltd (CH) 2022-10-19 EP disclosed
EP-3856867-B1 TREATMENT OF IRON SULPHIDE DEPOSITS RHODIA OPERATIONS (FR) 2022-06-15 EP disclosed
US-20210395123-A1 TREATMENT OF IRON SULPHIDE DEPOSITS RHODIA OPERATIONS (FR) 2021-12-23 US disclosed
US-20210317357-A1 Amorphous Dithiazine Dissolution Formulation and Method for Using the Same CLARIANT INTERNATIONAL LTD. (CH) 2021-10-14 US disclosed
EP-0215562-B1 BIOCIDAL MIXTUREAND METHOD FOR THE TREATMENT OF WATER Albright &amp; Wilson Limited (GB) 1990-09-19 EP disclosed
EP-0385676-A1 Biocidal compositions and treatments Albright &amp; Wilson Limited (GB) 1990-09-05 EP disclosed
EP-0385801-A1 Biocidal compositions and treatments Albright &amp; Wilson Limited (GB) 1990-09-05 EP disclosed
EP-0380359-A1 Biocidal compositions and treatments Albright &amp; Wilson Limited (GB) 1990-08-01 EP disclosed
US-4738953-A ETHER-SUBSTITUTED MONOSACCHARIDE AND COMPATIBLE DRUG GREENWICH PHARMACEUTICALS INCORPORATED (US) 1988-04-19 US disclosed
US-4735934-A WITH REACTION PRODUCT OF MONOSACCHARIDE AND AMINE GREENWICH PHARMACEUTICALS INCORPORATED (US) 1988-04-05 US disclosed
EP-0215562-A1 Biocidal mixtureand method for the treatment of water Albright &amp; Wilson Limited (GB) 1987-03-25 EP disclosed
US-4440665-A AMPHOTERIC-NONIONIC MIXTURES ALBRIGHT & WILSON LIMITED (GB) 1984-04-03 US disclosed
US-4243549-A Concentrated aqueous surfactant compositions ALBRIGHT & WILSON LTD. (GB) 1981-01-06 US disclosed