Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.65 |
| ▸ | MEN1 | O00255 | 3/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.65 |
| ▸ | BLM | P54132 | 1/20 | 0.65 |
| ▸ | HBB | P68871 | 1/20 | 0.65 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.65 |
| ▸ | TSHR | P16473 | 5/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.57 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.48 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 6/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL504353 | 1.00 | LMNA (0.65) | LMNAMEN1KMT2ABLMHBB | |
| SCHEMBL2371134 | 1.00 | LMNA (0.65) | LMNAMEN1KMT2ABLMHBB | |
| SCHEMBL2370652 | 1.00 | LMNA (0.65) | LMNAMEN1KMT2ABLMHBB | |
| SCHEMBL2371891 | 1.00 | LMNA (0.65) | LMNAMEN1KMT2ABLMHBB | |
| SCHEMBL2372027 | 1.00 | LMNA (0.65) | LMNAMEN1KMT2ABLMHBB | |
| SCHEMBL2371874 | 1.00 | LMNA (0.65) | LMNAMEN1KMT2ABLMHBB | |
| SCHEMBL5828245 | 1.00 | LMNA (0.65) | LMNAMEN1KMT2ABLMHBB | |
| SCHEMBL2380101 | 1.00 | LMNA (0.65) | LMNAMEN1KMT2ABLMHBB | |
| SCHEMBL11701621 | 1.00 | LMNA (0.65) | LMNAMEN1KMT2ABLMHBB | |
| SCHEMBL2371273 | 1.00 | LMNA (0.65) | LMNAMEN1KMT2ABLMHBB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230065014-A1 | Nitro-Fatty Acid-Containing Microbubbles and Uses Therefor | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION | 2023-03-02 | — | — | US | claimed |
| WO-2021146428-A9 | NITRO-FATTY ACID-CONTAINING MICROBUBBLES AND USED THEREFOR | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2021-08-19 | — | — | WO | claimed |
| WO-2021146428-A1 | NITRO-FATTY ACID-CONTAINING MICROBUBBLES AND USED THEREFOR | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2021-07-22 | — | — | WO | claimed |
| US-20230065014-A1 | Nitro-Fatty Acid-Containing Microbubbles and Uses Therefor | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION | 2023-03-02 | — | — | US | disclosed |
| US-20210395184-A1 | VINYL SUBSTITUTED FATTY ACIDS | COMPLEXA, INC. (US) | 2021-12-23 | — | — | US | disclosed |
| WO-2021146428-A9 | NITRO-FATTY ACID-CONTAINING MICROBUBBLES AND USED THEREFOR | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2021-08-19 | — | — | WO | disclosed |
| WO-2021146428-A1 | NITRO-FATTY ACID-CONTAINING MICROBUBBLES AND USED THEREFOR | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2021-07-22 | — | — | WO | disclosed |
| US-20200308096-A1 | VINYL SUBSTITUTED FATTY ACIDS | COMPLEXA, INC. (US) | 2020-10-01 | — | — | US | disclosed |
| EP-2280928-B1 | VINYL SUBSTITUTED FATTY ACIDS | COMPLEXA INC (US) | 2018-07-25 | — | — | EP | disclosed |
| US-20170369419-A1 | VINYL SUBSTITUTED FATTY ACIDS | COMPLEXA, INC. (US) | 2017-12-28 | — | — | US | disclosed |
| US-9790167-B2 | Vinyl substituted fatty acids | COMPLEXA, INC. (US) | 2017-10-17 | — | — | US | disclosed |
| US-20140256814-A1 | HETEROATOM CONTAINING SUBSTITUTED FATTY ACIDS | COMPLEXA, INC. (US) | 2014-09-11 | — | — | US | disclosed |
| US-20130012583-A1 | VINYL SUBSTITUTED FATTY ACIDS | UNIVERSITY OF PITTSBURGH-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2013-01-10 | — | — | US | disclosed |
| EP-2483233-A2 | HETEROATOM CONTAINING SUBSTITUTED FATTY ACIDS | Miller, Raymond A. (US) | 2012-08-08 | — | — | EP | disclosed |
| CN-102083787-A | Vinyl substituted fatty acids | COMPLEXA INC | 2011-06-01 | — | — | CN | disclosed |
| WO-2011041639-A2 | HETEROATOM CONTAINING SUBSTITUTED FATTY ACIDS | MILLER RAYMOND A (US) | 2011-04-07 | — | — | WO | disclosed |
| US-20110082206-A1 | HETEROATOM CONTAINING SUBSTITUTED FATTY ACIDS | COMPLEXA, INC. | 2011-04-07 | — | — | US | disclosed |
| EP-2280928-A2 | VINYL SUBSTITUTED FATTY ACIDS | Complexa Inc. (US) | 2011-02-09 | — | — | EP | disclosed |
| US-20090326070-A1 | VINYL SUBSTITUTED FATTY ACIDS | COMPLEXA INC. (US) | 2009-12-31 | — | — | US | disclosed |
| WO-2009134383-A2 | VINYL SUBSTITUTED FATTY ACIDS | COMPLEXA INC. (US) | 2009-11-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200308096-A1 | VINYL SUBSTITUTED FATTY ACIDS | FFAR2, ELOVL1, FFAR4 | LMNA 1075/4885MEN1 4807/4885KMT2A 2230/4885 |
| US-20170369419-A1 | VINYL SUBSTITUTED FATTY ACIDS | FFAR2, ELOVL1, FFAR4 | LMNA 1075/4885MEN1 4807/4885KMT2A 2230/4885 |
| US-20140256814-A1 | HETEROATOM CONTAINING SUBSTITUTED FATTY ACIDS | FFAR2, FFAR1, FFAR4 | LMNA 1975/4885MEN1 4870/4885KMT2A 2418/4885 |
| US-20130012583-A1 | VINYL SUBSTITUTED FATTY ACIDS | FFAR2, ELOVL1, FFAR4 | LMNA 1075/4885MEN1 4807/4885KMT2A 2230/4885 |
| US-20230065014-A1 | Nitro-Fatty Acid-Containing Microbubbles and Uses Therefor | ALOX15, ALOX15B, ALOX12 | LMNA 2286/4885MEN1 2908/4885KMT2A 4551/4885 |
| US-20210395184-A1 | VINYL SUBSTITUTED FATTY ACIDS | FFAR2, ELOVL1, FFAR4 | LMNA 1075/4885MEN1 4807/4885KMT2A 2230/4885 |
| US-20090326070-A1 | VINYL SUBSTITUTED FATTY ACIDS | FFAR2, ELOVL1, FFAR4 | LMNA 1075/4885MEN1 4807/4885KMT2A 2230/4885 |
| US-20110082206-A1 | HETEROATOM CONTAINING SUBSTITUTED FATTY ACIDS | FFAR2, FFAR1, FFAR4 | LMNA 1975/4885MEN1 4870/4885KMT2A 2418/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.