Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DOT1L | Q8TEK3 | 5/20 | 0.52 |
| ▸ | AHCY | P23526 | 2/20 | 0.44 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.42 |
| ▸ | PRKACA | P17612 | 3/20 | 0.41 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10887920 | 0.80 | DOT1L (0.62) | DOT1LAHCYPLA2G2APRKACA | |
| SCHEMBL16574770 | 0.71 | DOT1L (0.60) | DOT1LAHCYPLA2G2APRKACA | |
| SCHEMBL29540124 | 0.71 | DOT1L (0.61) | DOT1LAHCYPRKACA | |
| SCHEMBL5943937 | 0.69 | DOT1L (0.52) | DOT1LAHCYPRKACA | |
| SCHEMBL10886925 | 0.69 | DOT1L (0.48) | DOT1LAHCY | |
| SCHEMBL14905923 | 0.68 | DOT1L (0.60) | DOT1LAHCYPLA2G2A | |
| SCHEMBL10885233 | 0.68 | AHCY (0.62) | DOT1LAHCYPLA2G2APRKACA | |
| SCHEMBL10887149 | 0.68 | AHCY (0.62) | DOT1LAHCYPLA2G2APRKACA | |
| SCHEMBL16578293 | 0.68 | DOT1L (0.68) | DOT1LAHCYPRKACA | |
| SCHEMBL5944004 | 0.67 | DOT1L (0.61) | DOT1LAHCYPRKACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0071926-A1 | New ribofuranuronic acid derivatives, processes for preparation thereof and pharmaceutical compositions thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-02-16 | — | — | EP | disclosed |