Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | MMP1 | P03956 | 1/20 | 0.53 |
| ▸ | MMP3 | P08254 | 1/20 | 0.53 |
| ▸ | MMP7 | P09237 | 1/20 | 0.53 |
| ▸ | MMP9 | P14780 | 1/20 | 0.53 |
| ▸ | MMP13 | P45452 | 1/20 | 0.53 |
| ▸ | SDCBP | O00560 | 2/20 | 0.51 |
| ▸ | SDC2 | P34741 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | CTSL | P07711 | 1/20 | 0.50 |
| ▸ | CTSB | P07858 | 1/20 | 0.50 |
| ▸ | CTSK | P43235 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.46 |
| ▸ | FPR2 | P25090 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11061860 | 1.00 | MMP2 (0.53) | MMP2TSHRMMP1MMP3MMP7 | |
| SCHEMBL11573752 | 0.98 | MMP2 (0.51) | MMP2TSHRMMP1MMP3MMP7 | |
| SCHEMBL11198241 | 0.85 | KIF11 (0.46) | MEN1KMT2ALMNAFPR2MAPT | |
| SCHEMBL11198240 | 0.85 | KIF11 (0.46) | MEN1KMT2ALMNAFPR2MAPT | |
| SCHEMBL11066794 | 0.85 | CTSL (0.50) | MMP2TSHRMMP1MMP3MMP7 | |
| SCHEMBL11193286 | 0.83 | MMP9 (0.51) | MMP2MMP1MMP3MMP7MMP9 | |
| SCHEMBL11196494 | 0.83 | ADAMTS4 (0.51) | MMP2TSHRMMP9MEN1KMT2A | |
| SCHEMBL11196490 | 0.83 | ADAMTS4 (0.51) | MMP2TSHRMMP9MEN1KMT2A | |
| SCHEMBL11193293 | 0.83 | MMP9 (0.51) | MMP2MMP1MMP3MMP7MMP9 | |
| SCHEMBL11198663 | 0.83 | FPR2 (0.50) | TSHRSDCBPSDC2CTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4243819-A | Substituted amino acids | ZOECON CORPORATION (US) | 1981-01-06 | — | — | US | claimed |
| US-4411912-A | Insecticidal isovaleric acid esters | ZOECON CORPORATION (US) | 1983-10-25 | — | — | US | disclosed |
| US-4243819-A | Substituted amino acids | ZOECON CORPORATION (US) | 1981-01-06 | — | — | US | disclosed |
| US-4231953-A | Fluoro substituted aryl esters and thiolesters of amino acids | ZOECON CORPORATION (US) | 1980-11-04 | — | — | US | disclosed |
| US-4226872-A | Pyridyl esters of α-substituted amino acids | ZOECON CORPORATION (US) | 1980-10-07 | — | — | US | disclosed |