SCHEMBL1119940

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1202001	0.79	NOTUM (0.42)	METAP2KMT2AMEN1POLBNOTUM
	SCHEMBL27606211	0.79	METAP2 (0.42)	METAP2KMT2AMEN1LMNARAB9A
	SCHEMBL27584582	0.79	METAP2 (0.42)	METAP2KMT2AMEN1LMNAPOLB
	SCHEMBL4047707	0.79	AKT1 (0.42)	METAP2KMT2AMEN1LMNAPOLB
	SCHEMBL4046110	0.79	RAB9A (0.37)	KMT2AMEN1POLBRAB9ANPC1
	SCHEMBL1317405	0.79	NPC1 (0.46)	KMT2AMEN1LMNAPOLBRAB9A
	SCHEMBL27554388	0.79	METAP2 (0.47)	METAP2KMT2AMEN1LMNANOTUM
	SCHEMBL27584597	0.79	KIF11 (0.42)	KMT2AMEN1LMNAPOLBNOTUM
	SCHEMBL63014	0.78	RAB9A (0.41)	METAP2KMT2AMEN1POLBNOTUM
	SCHEMBL7179987	0.77	LMNA (0.42)	KMT2ALMNANOTUMRAB9ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.