Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6674978 | 0.81 | KDM4E (0.49) | ALOX5OPRM1OPRK1KDM4ELMNA | |
| Hydrochloric Acid SCHEMBL27535166 | 0.80 | KDM4E (0.48) | ALOX5OPRM1OPRK1KDM4ELMNA | |
| SCHEMBL2456760 | 0.76 | ALOX5 (0.50) | ALOX5LMNANPSR1TP53POLB | |
| Hydrochloric Acid SCHEMBL1281247 | 0.74 | ALOX5 (0.49) | ALOX5LMNANPSR1TP53POLB | |
| SCHEMBL9853132 | 0.74 | ALOX5 (0.45) | ALOX5OPRM1OPRK1KDM4ELMNA | |
| SCHEMBL11202646 | 0.73 | KDM4E (0.38) | ALOX5OPRM1OPRK1KDM4ELMNA | |
| SCHEMBL11202255 | 0.72 | LMNA (0.43) | OPRM1OPRK1LMNANPSR1TP53 | |
| SCHEMBL9130249 | 0.72 | ALOX5 (0.39) | ALOX5KDM4ELMNAPOLBCES2 | |
| SCHEMBL2376360 | 0.72 | OPRM1 (0.44) | ALOX5OPRM1OPRK1KDM4ELMNA | |
| SCHEMBL2018408 | 0.71 | OPRM1 (0.44) | ALOX5OPRM1OPRK1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0068171-A1 | Dihydropyridine compounds | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1983-01-05 | — | — | EP | disclosed |