Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | RBP1 | P09455 | 1/20 | 0.38 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | G6PC1 | P35575 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4438409 | 0.88 | LMNA (0.41) | LMNAL3MBTL1OPRK1SLC6A2SLC6A4 | |
| SCHEMBL4440878 | 0.88 | LMNA (0.41) | LMNAL3MBTL1OPRK1SLC6A2SLC6A4 | |
| SCHEMBL4448653 | 0.88 | LMNA (0.41) | LMNAL3MBTL1OPRK1SLC6A2SLC6A4 | |
| SCHEMBL13986004 | 0.81 | LMNA (0.43) | LMNAL3MBTL1OPRK1SLC6A2SLC6A4 | |
| SCHEMBL4436800 | 0.79 | CHRNB2 (0.43) | LMNAL3MBTL1TSHRALDH1A1ADAM17 | |
| SCHEMBL6674978 | 0.79 | KDM4E (0.49) | LMNAOPRK1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL14017766 | 0.77 | ADRA2B (0.50) | OPRK1SLC6A2SLC6A4SLC6A3KCNH2 | |
| Hydrochloric Acid SCHEMBL27535166 | 0.77 | KDM4E (0.48) | LMNAOPRK1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL13452589 | 0.77 | ADRA2B (0.50) | OPRK1SLC6A2SLC6A4SLC6A3KCNH2 | |
| SCHEMBL11198448 | 0.75 | OPRK1 (0.41) | LMNAOPRK1SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0068171-A1 | Dihydropyridine compounds | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1983-01-05 | — | — | EP | disclosed |