Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 3/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1119995 | 0.84 | RAB9A (0.43) | RAB9AKMT2AMEN1L3MBTL1ALDH1A1 | |
| SCHEMBL1120131 | 0.82 | HRH3 (0.33) | RAB9AKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL1120255 | 0.80 | CASP3 (0.42) | RAB9AKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL1120331 | 0.79 | GPR119 (0.44) | FAAH | |
| SCHEMBL12074812 | 0.79 | KMT2A (0.43) | RAB9AKMT2AMEN1L3MBTL1ALDH1A1 | |
| SCHEMBL2593942 | 0.79 | SMYD3 (0.33) | HCRTR2 | |
| SCHEMBL1966097 | 0.78 | MTNR1A (0.34) | RAB9AALDH1A1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL1966094 | 0.78 | MTNR1A (0.34) | RAB9AALDH1A1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL3431702 | 0.78 | MTNR1A (0.34) | RAB9AALDH1A1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL17350987 | 0.78 | GRM2 (0.39) | KMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2280965-B1 | THIAZOL-4-CARBOXYLIC ACID ESTERS AND THIOESTERS AS PLANT PROTECTION AGENTS | BAYER CROPSCIENCE AG (DE) | 2012-08-29 | — | — | EP | disclosed |
| EP-2280965-A1 | THIAZOL-4-CARBOXYLIC ACID ESTERS AND THIOESTERS AS PLANT PROTECTION AGENTS | BAYER CROPSCIENCE AG (DE) | 2011-02-09 | — | — | EP | disclosed |
| WO-2009132785-A1 | THIAZOL-4-CARBOXYLIC ACID ESTERS AND THIOESTERS AS PLANT PROTECTION AGENTS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT | 2009-11-05 | — | — | WO | disclosed |