Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | NCF1 | P14598 | 2/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.41 |
| ▸ | BTK | Q06187 | 1/20 | 0.40 |
| ▸ | LTB4R | Q15722 | 6/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2300904 | 0.85 | RAB9A (0.57) | RAB9AMEN1KMT2ANPC1ALDH1A1 | |
| SCHEMBL5331564 | 0.83 | SOAT1 (0.50) | RAB9AMEN1KMT2ALTB4R | |
| SCHEMBL30834594 | 0.76 | LTB4R (0.54) | LTB4R | |
| SCHEMBL11204151 | 0.76 | LTB4R (0.44) | RAB9AMEN1KMT2AHTR7LTB4R | |
| SCHEMBL6377203 | 0.76 | TRPV3 (0.41) | MEN1KMT2AALDH1A1NCF1SMN1; SMN2 | |
| SCHEMBL28051936 | 0.76 | RAB9A (0.50) | RAB9AMEN1KMT2ANPC1ALDH1A1 | |
| SCHEMBL6377587 | 0.76 | HTR7 (0.61) | RAB9ANPC1MAPK1NCF1ADORA1 | |
| SCHEMBL8987210 | 0.74 | LTB4R (0.58) | LTB4R | |
| SCHEMBL8987412 | 0.74 | LTB4R (0.58) | LTB4R | |
| SCHEMBL7565905 | 0.74 | NCF1 (0.42) | NCF1HTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0090353-A1 | 2-Pyridone derivatives, method for their preparation and pharmaceutical compositions containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1983-10-05 | — | — | EP | disclosed |