Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | RAD52 | P43351 | 1/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.36 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.36 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.36 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.36 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.36 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7016620 | 0.88 | KIF11 (0.42) | ALDH1A1KMT2AMEN1LMNAKDM4E | |
| SCHEMBL7008377 | 0.81 | PRKAB2 (0.42) | PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3 | |
| SCHEMBL7014803 | 0.76 | KIF11 (0.52) | ALDH1A1DRD3KMT2AMEN1LMNA | |
| SCHEMBL11204174 | 0.74 | ALDH1A1 (0.47) | ALDH1A1DRD3KMT2AMEN1LMNA | |
| SCHEMBL7015614 | 0.74 | LMNA (0.75) | ALDH1A1DRD3KMT2AMEN1LMNA | |
| SCHEMBL7196066 | 0.73 | PRKAB2 (0.38) | KDM4ENPC1GAAPRKAB2PRKAG1 | |
| SCHEMBL7013585 | 0.71 | KDM4E (0.42) | ALDH1A1KMT2AMEN1LMNAKDM4E | |
| SCHEMBL7011748 | 0.70 | ALOX5 (0.46) | ALDH1A1KMT2AMEN1LMNAKDM4E | |
| SCHEMBL9379704 | 0.69 | ALDH1A1 (0.58) | ALDH1A1DRD3KMT2AMEN1LMNA | |
| SCHEMBL11208613 | 0.68 | GAA (0.47) | ALDH1A1DRD3KMT2AMEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1313708-A1 | QUINOLINE ANTIBACTERIAL COMPOUNDS AND METHODS OF USE THEREOF | CHIRON CORPORATION (US) | 2003-05-28 | — | — | EP | disclosed |
| WO-2002018345-A1 | QUINOLINE ANTIBACTERIAL COMPOUNDS AND METHODS OF USE THEREOF | CHIRON CORPORATION (US) | 2002-03-07 | — | — | WO | disclosed |