Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.55 |
| ▸ | DRD2 | P14416 | 1/20 | 0.55 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.50 |
| ▸ | DRD4 | P21917 | 1/20 | 0.49 |
| ▸ | DRD3 | P35462 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | NOS3 | P29474 | 1/20 | 0.47 |
| ▸ | NOS1 | P29475 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | CASP4 | P49662 | 1/20 | 0.47 |
| ▸ | CASP5 | P51878 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11203954 | 0.92 | SIGMAR1 (0.58) | SIGMAR1 | |
| SCHEMBL10856538 | 0.86 | GAA (0.58) | SIGMAR1DRD4MAPTMEN1ALDH1A1 | |
| SCHEMBL10852018 | 0.80 | HTR1A (0.50) | HTR1ADRD2SIGMAR1DRD3 | |
| SCHEMBL11199379 | 0.79 | HTR1A (0.59) | HTR1ADRD2SIGMAR1DRD3 | |
| SCHEMBL10856395 | 0.78 | HTR1A (0.54) | HTR1ADRD2SIGMAR1DRD3 | |
| SCHEMBL16825857 | 0.78 | HTR1A (0.55) | HTR1ADRD2SIGMAR1DRD4DRD3 | |
| SCHEMBL13150782 | 0.74 | SLC6A3 (0.83) | HTR1ADRD2SIGMAR1MAPTNPSR1 | |
| SCHEMBL7264546 | 0.74 | SLC6A3 (0.83) | HTR1ADRD2SIGMAR1MAPTNPSR1 | |
| SCHEMBL14407778 | 0.74 | SLC6A3 (0.83) | HTR1ADRD2SIGMAR1MAPTNPSR1 | |
| SCHEMBL6056974 | 0.74 | SLC6A3 (0.83) | HTR1ADRD2SIGMAR1MAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4421753-A | HYPOTENSIVE AGENTS | AMERICAN CYANAMID COMPANY (US) | 1983-12-20 | — | — | US | claimed |