Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.36 |
| ▸ | ALPL | P05186 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | AMPD2 | Q01433 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10913138 | 0.97 | LMNA (0.41) | LMNAPOLBOPRK1SIGMAR1KMT2A | |
| SCHEMBL10912812 | 0.81 | THRB (0.38) | LMNAPOLBOPRK1KMT2AALDH1A1 | |
| SCHEMBL10908685 | 0.78 | OPRK1 (0.34) | LMNAPOLBOPRK1SIGMAR1KMT2A | |
| SCHEMBL7456872 | 0.74 | LMNA (0.42) | LMNAPOLBOPRK1SIGMAR1ALDH1A1 | |
| SCHEMBL27422400 | 0.72 | SIGMAR1 (0.46) | SIGMAR1ALDH1A1NPSR1 | |
| SCHEMBL11098244 | 0.71 | OPRK1 (0.50) | LMNAPOLBOPRK1NPC1RAB9A | |
| SCHEMBL10818495 | 0.70 | OPRK1 (0.52) | LMNAPOLBOPRK1NPC1RAB9A | |
| SCHEMBL22602392 | 0.69 | OPRK1 (0.39) | OPRK1SIGMAR1KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL7458620 | 0.68 | OPRK1 (0.57) | LMNAPOLBOPRK1SIGMAR1KMT2A | |
| SCHEMBL8509802 | 0.67 | USP14 (0.47) | SIGMAR1KMT2AALDH1A1L3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0095262-A1 | Azabicycloalkane derivatives, their preparation and medicaments containing them | BEECHAM GROUP PLC (GB) | 1983-11-30 | — | — | EP | disclosed |