Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | TSPO | P30536 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | XBP1 | P17861 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | AKT1 | P31749 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL78109 | 0.81 | SIGMAR1 (0.42) | LMNAMAPTSMN1; SMN2GAATSPO | |
| SCHEMBL7559113 | 0.76 | GABRA1 (0.44) | ELANELMNAMAPTSMN1; SMN2HPGD | |
| SCHEMBL204643 | 0.75 | TSHR (0.50) | LMNAHPGDALDH1A1TSHRKMT2A | |
| SCHEMBL11790232 | 0.73 | TSPO (0.38) | LMNAMAPTSMN1; SMN2GAATSPO | |
| SCHEMBL11483948 | 0.73 | LMNA (0.37) | LMNAMAPTSMN1; SMN2GAATSPO | |
| SCHEMBL11478893 | 0.73 | POLB (0.41) | LMNASMN1; SMN2HPGDALDH1A1TP53 | |
| SCHEMBL27961101 | 0.73 | ALDH1A1 (0.46) | ELANELMNAMAPTSMN1; SMN2GAA | |
| SCHEMBL10384846 | 0.72 | LMNA (0.36) | LMNAMAPTSMN1; SMN2GAATSPO | |
| SCHEMBL22504351 | 0.71 | MAPT (0.36) | ELANEMAPTALDH1A1TP53TSHR | |
| SCHEMBL11511457 | 0.71 | C5AR1 (0.38) | SMN1; SMN2HPGDTSHRKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0012452-B1 | PHOSPHORIC ACID ESTERS AND THEIR USE IN PESTICIDAL COMPOSITIONS | BAYER AG (DE) | 1983-02-09 | — | — | EP | disclosed |
| EP-0000127-B1 | INSECTICIDAL AND ACARICIDAL COMPOSITIONS, THEIR MANUFACTURE AND THEIR USE | BAYER AG (DE) | 1982-10-20 | — | — | EP | disclosed |
| EP-0012452-A2 | Phosphoric acid esters and their use in pesticidal compositions | BAYER AG (DE) | 1980-06-25 | — | — | EP | disclosed |
| EP-0000127-A1 | Insecticidal and acaricidal compositions, their manufacture and their use | BAYER AG (DE) | 1979-01-10 | — | — | EP | disclosed |