SCHEMBL1120966

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14394544	0.89	LMNA (0.51)	LMNAKDM4EABCB11ESR1CYP3A4
	SCHEMBL1120944	0.76	CYP1A2 (0.41)	LMNAKDM4ECYP3A4ADRA2ACYP2C9
	SCHEMBL1121246	0.75	HDAC8 (0.39)	LMNAESR1CYP3A4CYP2C9APP
	SCHEMBL177167	0.72	LMNA (0.64)	LMNAKDM4EESR1CYP3A4SLC6A3
	Hydrochloric Acid SCHEMBL27999837	0.71	LMNA (0.61)	LMNAKDM4EESR1CYP3A4SLC6A3
	SCHEMBL1120979	0.69	LMNA (0.51)	LMNACYP3A4ADRA2ACYP2C9TSHR
	SCHEMBL1120955	0.68	MAPT (0.40)	LMNAAPPALDH1A1MAPTRXRA
	SCHEMBL8936885	0.68	HSD17B10 (0.63)	LMNAKDM4EESR1CYP3A4TSHR
	SCHEMBL1121093	0.67	APP (0.32)	KDM4ETSHRAPP
	SCHEMBL8581401	0.66	LMNA (0.55)	LMNAKDM4EESR1CYP3A4SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.