SCHEMBL1120944

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1121246	0.88	HDAC8 (0.39)	CYP1A2CYP3A4G6PC1CYP2C19APP
	SCHEMBL1120982	0.81	MAPT (0.49)	CYP1A2CYP3A4CYP2C19TSHRALDH1A1
	SCHEMBL1120955	0.77	MAPT (0.40)	NR3C2APPCYP2D6LMNAALDH1A1
	SCHEMBL1120966	0.76	LMNA (0.40)	CYP3A4APPTSHRLMNAALDH1A1
	SCHEMBL1121145	0.74	KMT2A (0.39)	CYP2C19APPTSHRCYP2D6KCNH2
	SCHEMBL11271139	0.74	CYP2C19 (0.64)	CYP1A2CYP2C19TSHRCYP2D6LMNA
	SCHEMBL9446230	0.72	NR3C2 (0.59)	NR3C2KCNA3CYP2C19TSHRALDH1A1
	SCHEMBL1121025	0.72	APP (0.33)	APPTSHRHTR2ADRD1DRD3
	SCHEMBL28470935	0.71	ALDH1A1 (0.53)	CYP1A2CYP3A4CYP2C19TSHRCYP2D6
	Iodide SCHEMBL11397726	0.71	TSHR (0.38)	CYP1A2NR3C2KCNA3TSHRCYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.