SCHEMBL1121100

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL28937837	0.84	KDM4E (0.42)	MAPK1KDM4ETDP1HTTL3MBTL1
	SCHEMBL29270323	0.81	MEN1 (0.44)	MAPK1KDM4ETDP1HTTL3MBTL1
	SCHEMBL10715305	0.73	HTT (0.50)	TDP1HTTL3MBTL1ALDH1A1CYP1A2
	SCHEMBL9381367	0.73	KCNA5 (0.44)	HTTL3MBTL1ALDH1A1CYP1A2KMT2A
	SCHEMBL1121145	0.72	KMT2A (0.39)	HTTKMT2AMEN1NPC1RAB9A
	SCHEMBL1275299	0.72	EGFR (0.44)	MAPK1KDM4ETDP1L3MBTL1ALDH1A1
	SCHEMBL17195664	0.71	MAPT (0.56)	MAPK1KDM4ETDP1L3MBTL1ALDH1A1
	SCHEMBL228886	0.70	CYP2D6 (0.57)	MAPK1KDM4ECYP1A2LMNASMN1; SMN2
	SCHEMBL28366068	0.68	CYP2D6 (0.65)	MAPK1KDM4ECYP1A2LMNASMN1; SMN2
	SCHEMBL1120979	0.68	LMNA (0.51)	TDP1HTTL3MBTL1ALDH1A1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.