SCHEMBL1121145

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1120955	0.85	MAPT (0.40)	KCNA5CYP2D6KCNE1APPHTT
	SCHEMBL9381367	0.83	KCNA5 (0.44)	KMT2APOLBKCNA5KCNH2CYP2D6
	SCHEMBL1120975	0.81	APP (0.34)	KCNA5APPRAB9AKDR
	SCHEMBL1121114	0.78	ALDH1A1 (0.37)	KMT2AMEN1NPC1RAB9A
	SCHEMBL1121025	0.77	APP (0.33)	APPTSHRDRD2DRD3
	SCHEMBL1120944	0.74	CYP1A2 (0.41)	KMT2AKCNH2CYP2D6APPTSHR
	SCHEMBL1121093	0.73	APP (0.32)	APPTSHR
	SCHEMBL1121246	0.72	HDAC8 (0.39)	CYP2D6APPCYP2C19
	SCHEMBL1120982	0.72	MAPT (0.49)	KMT2AKCNA5TSHRMEN1CYP2C19
	SCHEMBL1121100	0.72	MAPK1 (0.39)	KMT2APOLBKCNH2CYP2D6TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.