SCHEMBL11214533

SCHEMBL11214533

Oc1ccc(-c2[c]ccc(O)c2-c2ccccc2)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP3 P08254 1/20 0.48
BCL2L1 Q07817 1/20 0.48
ESR1 P03372 9/20 0.45
ESR2 Q92731 8/20 0.45
PDE4A P27815 2/20 0.41
PDE4B Q07343 2/20 0.41
PDE4C Q08493 2/20 0.41
PDE4D Q08499 2/20 0.41
ALOX5 P09917 3/20 0.38
RPS6KA3 P51812 1/20 0.38
MEN1 O00255 4/20 0.38
KMT2A Q03164 4/20 0.38
CYP1A2 P05177 1/20 0.37
CYP3A4 P08684 1/20 0.37
CYP2D6 P10635 1/20 0.37
CYP2C9 P11712 1/20 0.37
HSD17B1 P14061 1/20 0.37
CYP2B6 P20813 1/20 0.37
CYP2C19 P33261 1/20 0.37
HSD17B2 P37059 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1812352 0.76 ESR1 (0.39) MMP3BCL2L1ESR1ESR2ALOX5
SCHEMBL7291535 0.75 ESR1 (0.42) MMP3BCL2L1ESR1ESR2ALOX5
SCHEMBL10402560 0.75 ALOX5 (0.40) MMP3BCL2L1ESR2PDE4APDE4B
SCHEMBL15658894 0.75 BACE1 (0.39) MMP3BCL2L1ESR1ESR2PDE4A
SCHEMBL6399757 0.74 SENP1 (0.45) MMP3BCL2L1ESR1ESR2PDE4A
SCHEMBL20323048 0.73 MMP3 (0.78) MMP3BCL2L1ESR1ESR2PDE4A
SCHEMBL20323157 0.73 MMP3 (0.78) MMP3BCL2L1ESR1ESR2PDE4A
SCHEMBL22147379 0.73 MMP3 (0.78) MMP3BCL2L1ESR1ESR2PDE4A
SCHEMBL22147351 0.73 MMP3 (0.78) MMP3BCL2L1ESR1ESR2PDE4A
SCHEMBL28979295 0.73 MMP3 (0.78) MMP3BCL2L1ESR1ESR2PDE4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0043997-A2 Flame retarding agent for polycarbonates Mobay Chemical Corporation (US) 1982-01-20 EP disclosed