SCHEMBL1812352

SCHEMBL1812352

Oc1ccc(-c2[c]ccc(-c3ccc(O)cc3)c2-c2ccc(O)cc2)cc1

nearest known ligand 0.39

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 4/20 0.39
ESR2 Q92731 2/20 0.39
MMP3 P08254 2/20 0.38
MMP2 P08253 1/20 0.38
SENP1 Q9P0U3 1/20 0.38
MGAM O43451 2/20 0.36
GAA P10253 2/20 0.36
SI P14410 2/20 0.36
MGAM2 Q2M2H8 2/20 0.36
ABL1 P00519 1/20 0.35
ABCB1 P08183 1/20 0.35
BCR P11274 1/20 0.35
USP7 Q93009 5/20 0.35
ALOX5 P09917 1/20 0.34
RPS6KA3 P51812 1/20 0.34
BCL2L1 Q07817 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9559530 0.80 PTGS2 (0.36)
SCHEMBL2834322 0.80 PTGS2 (0.35)
SCHEMBL891578 0.79 LMNA (0.36) ALOX5BCL2L1
SCHEMBL6399757 0.78 SENP1 (0.45) ESR1ESR2MMP3SENP1GAA
SCHEMBL11019765 0.78 SENP1 (0.45) ESR1ESR2MMP3MMP2SENP1
SCHEMBL11214533 0.76 MMP3 (0.48) ESR1ESR2MMP3ALOX5RPS6KA3
SCHEMBL7702832 0.74 MGAM (0.46) ESR2SENP1MGAMGAASI
SCHEMBL9559721 0.74 ADORA1 (0.36) ALOX5
SCHEMBL7708522 0.74 SENP1 (0.37) ESR1ESR2SENP1ALOX5
SCHEMBL6056277 0.73 ABL1 (0.45) ESR1ESR2MMP3ABL1ABCB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0021260-A1 Process for the preparation of thermoplastic, branched, aromatic polyphosphonates BAYER AG (DE) 1981-01-07 EP claimed
EP-3541778-A1 ELECTROCHEMICAL METHOD FOR PRODUCING ARYL ALKYL CARBONATES AND DIARYL CARBONATES Covestro Deutschland AG (DE) 2019-09-25 EP disclosed
WO-2018091370-A1 ELECTROCHEMICAL METHOD FOR PRODUCING ARYL ALKYL CARBONATES AND DIARYL CARBONATES COVESTRO DEUTSCHLAND AG (DE) 2018-05-24 WO disclosed
EP-2683551-A1 TRANSPARENT PLASTIC FILM THAT CAN BE ELECTROPLATED FOR PARTIAL ELECTROPLATING Bayer Intellectual Property GmbH (DE) 2014-01-15 EP disclosed
WO-2012120007-A1 TRANSPARENT PLASTIC FILM THAT CAN BE ELECTROPLATED FOR PARTIAL ELECTROPLATING BAYER MATERIALSCIENCE AG (DE) 2012-09-13 WO disclosed
EP-2496638-A1 POLYCARBONATE PLATES WITH IMPROVED FLAME RESISTANCE Bayer MaterialScience AG (DE) 2012-09-12 EP disclosed
EP-2496639-A1 POLYCARBONATE COMPOSITION HAVING IMPROVED FLAME RESISTANCE FOR EXTRUSION APPLICATIONS Bayer MaterialScience AG (DE) 2012-09-12 EP disclosed
EP-2496636-A2 MORE FLAME-RETARDANT POLYCARBONATE COMPOSITION FOR USE IN EXTRUDED PRODUCTS Bayer MaterialScience AG (DE) 2012-09-12 EP disclosed
WO-2011054862-A1 POLYCARBONATE PLATES WITH IMPROVED FLAME RESISTANCE BAYER MATERIALSCIENCE AG (DE) 2011-05-12 WO disclosed
WO-2011054865-A2 MORE FLAME-RETARDANT POLYCARBONATE COMPOSITION FOR USE IN EXTRUDED PRODUCTS BAYER MATERIALSCIENCE AG (DE) 2011-05-12 WO disclosed
EP-0129148-A1 Flame-resistant agents, their preparation and their use in rendering a polycarbonate flame-resistant BAYER AG (DE) 1984-12-27 EP disclosed
EP-0127842-A1 Diphenol monoesters of carboxylic acids, process for their preparation, their use in the preparation of polyester carbonates, polyester carbonates obtained according to the invention and flame-retardant moulding compounds containing these polyester carbonates BAYER AG (DE) 1984-12-12 EP disclosed
EP-0087038-A1 Use of lightly coloured polyphenylene sulphides in mixtures with thermoplastic polycarbonates and/or thermoplastic polyesters BAYER AG (DE) 1983-08-31 EP disclosed
EP-0062189-A1 Polycarbonate composition having impact strength Mobay Chemical Corporation (US) 1982-10-13 EP disclosed
EP-0034265-A2 Synergetically active mixtures of materials and their use in rendering polycarbonate moulding masses antistatic BAYER AG (DE) 1981-08-26 EP disclosed
EP-0028345-A1 Method of preparing thermoplastic aromatic polyphosphonates with thermal ageing resistance, and their use BAYER AG (DE) 1981-05-13 EP disclosed
EP-0023650-A2 Use of alkaline and earth-alkaline salts of alkyl-substituted aromatic sulphonic acids, phosphonic acids and acid esters of phosphoric acid as internal antistatic agents for films of polycarbonate BAYER AG (DE) 1981-02-11 EP disclosed
EP-0023291-A1 Stabilized thermoplastic moulding compositions based on polycarbonates, ABS polymers and phosphites BAYER AG (DE) 1981-02-04 EP disclosed
EP-0021260-A1 Process for the preparation of thermoplastic, branched, aromatic polyphosphonates BAYER AG (DE) 1981-01-07 EP disclosed
EP-0012356-A1 Thermoplastic elastomeric polymer composition BAYER AG (DE) 1980-06-25 EP disclosed