SCHEMBL6399757

SCHEMBL6399757

Cc1cc[c]c(-c2ccc(O)cc2)c1-c1ccc(O)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SENP1 Q9P0U3 1/20 0.45
USP7 Q93009 4/20 0.38
ESR1 P03372 4/20 0.37
ESR2 Q92731 4/20 0.37
ACHE P22303 1/20 0.34
PREP P48147 2/20 0.33
CELA1 Q9UNI1 1/20 0.33
ALOX5 P09917 1/20 0.33
PDE4A P27815 1/20 0.33
PDE4B Q07343 1/20 0.33
PDE4C Q08493 1/20 0.33
PDE4D Q08499 1/20 0.33
MMP3 P08254 1/20 0.32
BCL2L1 Q07817 1/20 0.32
KDM4E B2RXH2 1/20 0.32
ALDH1A1 P00352 1/20 0.32
LMNA P02545 1/20 0.32
GAA P10253 1/20 0.32
HPGD P15428 1/20 0.32
ALOX15 P16050 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7070227 0.80 BRD4 (0.36) ACHEKDM4EALDH1A1LMNAGAA
SCHEMBL1812352 0.78 ESR1 (0.39) SENP1USP7ESR1ESR2ALOX5
SCHEMBL7759583 0.77 ALDH1A1 (0.38) ALDH1A1
SCHEMBL7708522 0.77 SENP1 (0.37) SENP1ESR1ESR2PREPCELA1
SCHEMBL7702832 0.77 MGAM (0.46) SENP1ESR2PDE4APDE4BPDE4C
SCHEMBL3860568 0.74 SENP1 (0.42) SENP1USP7ESR1ESR2ACHE
SCHEMBL11214533 0.74 MMP3 (0.48) ESR1ESR2ALOX5PDE4APDE4B
SCHEMBL11758963 0.74 ALOX15 (0.42) SENP1ESR1ESR2GAAALOX15
SCHEMBL4367504 0.74 SENP1 (0.61) SENP1USP7ESR1ESR2ACHE
SCHEMBL29929295 0.74 SENP1 (0.61) SENP1USP7ESR1ESR2ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6955851-B2 Hydroxyaryl phosphine oxides, glycidyl ethers and epoxy compositions, composites and laminates derived therefrom PABU SERVICES, INC. (US) 2005-10-18 US disclosed
US-20050181393-A1 Novel chelating agents and highly luminescent and stable chelates and their use WALLAC OY (FI) 2005-08-18 US disclosed
US-6733698-B2 Mixture of mono-, bis- and tris-(hydroxyaryl) phosphine oxides useful to make polyglycidyl ethers or in epoxy compositions PABU SERVICES, INC. 2004-05-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050181393-A1 Novel chelating agents and highly luminescent and stable chelates and their use CLTA, CLTC, FOLH1 SENP1 2284/4885USP7 3509/4885ESR1 3991/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.