Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1B | P28222 | 2/20 | 0.44 |
| ▸ | HTR1A | P08908 | 15/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11220571 | 0.90 | HTR1A (0.45) | HTR1BHTR1AADRB2ADRB1ADRB3 | |
| SCHEMBL11071694 | 0.81 | PARP1 (0.44) | CYP1A2CYP3A4LMNAKDM4ECYP2C9 | |
| SCHEMBL11215196 | 0.77 | HTR1B (0.44) | HTR1BHTR1AADRB2ADRB1ADRB3 | |
| SCHEMBL5756503 | 0.74 | ALDH1A1 (0.51) | HTR1BHTR1AADRB2ADRB1ADRB3 | |
| SCHEMBL29989447 | 0.74 | ALDH1A1 (0.51) | HTR1BHTR1AADRB2ADRB1ADRB3 | |
| SCHEMBL1499352 | 0.74 | ALDH1A1 (0.51) | HTR1BHTR1AADRB2ADRB1ADRB3 | |
| SCHEMBL7884121 | 0.74 | ALDH1A1 (0.51) | HTR1BHTR1AADRB2ADRB1ADRB3 | |
| SCHEMBL9225959 | 0.72 | PDK1 (0.46) | HTR1BHTR1AADRB2ADRB1ADRB3 | |
| SCHEMBL9225971 | 0.72 | PDK1 (0.46) | HTR1BHTR1AADRB2ADRB1ADRB3 | |
| SCHEMBL9837429 | 0.70 | HTR1A (0.41) | HTR1ACYP1A2CYP3A4CYP2D6TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-57018677-A | — | — | None | — | — | JP | disclosed |
| JP-57018663-A | — | — | None | — | — | JP | disclosed |
| JP-57018676-A | — | — | None | — | — | JP | disclosed |
| JP-S5718677-A | PREPARATION OF NOVEL INDOLE DERIVATIVE | FUJIMOTO SEIYAKU KK | 1982-01-30 | — | — | JP | disclosed |
| JP-S5718676-A | NOVEL INDOLE DERIVATIVE AND ITS PREPARATION | FUJIMOTO SEIYAKU KK | 1982-01-30 | — | — | JP | disclosed |
| JP-S5718663-A | NOVEL PREPARATION OF PINDOLOL | FUJIMOTO SEIYAKU KK | 1982-01-30 | — | — | JP | disclosed |