Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 9/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 3/20 | 0.36 |
| ▸ | TACR1 | P25103 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10559798 | 0.81 | TACR1 (0.40) | HTR1ASLC6A4CYP2D6DRD2DRD4 | |
| SCHEMBL10558466 | 0.78 | NR3C1 (0.40) | CYP2D6MEN1KMT2AGRM2TACR1 | |
| SCHEMBL11220571 | 0.75 | HTR1A (0.45) | HTR1ACYP2D6DRD4DRD3MEN1 | |
| SCHEMBL11482581 | 0.72 | CA2 (0.47) | MEN1KMT2AGRM2MAPK1 | |
| SCHEMBL9835784 | 0.70 | PKM (0.43) | HTR1ASLC6A4DRD2DRD4DRD3 | |
| SCHEMBL9837332 | 0.70 | PKM (0.43) | HTR1ASLC6A4DRD2DRD4DRD3 | |
| SCHEMBL10558635 | 0.70 | PKM (0.43) | HTR1ASLC6A4DRD2DRD4DRD3 | |
| SCHEMBL9835778 | 0.70 | PKM (0.43) | HTR1ASLC6A4DRD2DRD4DRD3 | |
| SCHEMBL9837336 | 0.70 | PKM (0.43) | HTR1ASLC6A4DRD2DRD4DRD3 | |
| SCHEMBL11215201 | 0.70 | HTR1B (0.44) | HTR1ACYP2D6DRD4DRD3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0251938-B1 | STEREOSPECIFIC PROCESS FOR THE SYNTHESIS OF INDOLE DERIVATIVES | SANOFI (FR) | 1991-11-06 | — | — | EP | claimed |
| EP-0240107-B1 | THIANAPHTHENE DERIVATIVES, THEIR PRODUCTION AND USE | Sankyo Company Limited (JP) | 1991-08-21 | — | — | EP | disclosed |
| US-5021444-A | Anticoagulants | SANKYO COMPANY LIMITED (JP) | 1991-06-04 | — | — | US | disclosed |
| US-4847272-A | ANTICOAGULANTS | SANKYO COMPANY LIMITED (JP) | 1989-07-11 | — | — | US | disclosed |
| US-4806655-A | Process for the stereospecific synthesis of indole derivatives | SOCIETE ANONYME: SANOFI (FR) | 1989-02-21 | — | — | US | disclosed |