Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 16/20 | 0.45 |
| ▸ | HTR1B | P28222 | 2/20 | 0.45 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11215201 | 0.90 | HTR1B (0.44) | HTR1AHTR1BADRB2ADRB1CYP1A2 | |
| SCHEMBL11071694 | 0.90 | PARP1 (0.44) | CYP1A2CYP3A4LMNAKDM4ECYP2C9 | |
| SCHEMBL9225971 | 0.82 | PDK1 (0.46) | HTR1AHTR1BADRB2ADRB1CYP1A2 | |
| SCHEMBL9225959 | 0.82 | PDK1 (0.46) | HTR1AHTR1BADRB2ADRB1CYP1A2 | |
| SCHEMBL11875374 | 0.78 | HTR2B (0.47) | DRD4MAPK1 | |
| SCHEMBL11304628 | 0.77 | HTR2B (0.51) | MAPK1OPRK1SLC6A3 | |
| SCHEMBL11060976 | 0.77 | GRM2 (0.43) | MAPK1 | |
| SCHEMBL11067676 | 0.77 | GRM2 (0.39) | MAPK1 | |
| SCHEMBL11068306 | 0.77 | ADRB2 (0.44) | ADRB2ADRB1ADRB3NR3C1 | |
| SCHEMBL11069100 | 0.76 | HTR2B (0.42) | KDM4ETSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-57134463-A | — | — | None | — | — | JP | disclosed |
| JP-57169480-A | — | — | None | — | — | JP | disclosed |
| JP-56059772-A | — | — | None | — | — | JP | disclosed |
| JP-56053676-A | — | — | None | — | — | JP | disclosed |
| JP-56079689-A | — | — | None | — | — | JP | disclosed |
| JP-S57169480-A | PRODUCTION OF INDOLE DERIVATIVE | PAAMAKEMU ASIA:KK | 1982-10-19 | — | — | JP | disclosed |
| JP-S57134463-A | PREPARATION OF INDOLE DERIVATIVE | PAAMAKEMU ASIA:KK | 1982-08-19 | — | — | JP | disclosed |
| JP-S5679689-A | NOVEL OXAZOLIDINONE DERIVATIVE AND ITS PREPARATION | PAAMAKEMU ASIA:KK | 1981-06-30 | — | — | JP | disclosed |
| JP-S5659772-A | PREPARATION OF NOVEL 2-OXAZOLIDINONE DERIVATIVE | FUJIMOTO SEIYAKU KK | 1981-05-23 | — | — | JP | disclosed |
| JP-S5653676-A | NOVEL 2-OXAZOLIDINONE DERIVATIVE HAVING PHARMACEUTICAL ACTIVITY, AND ITS PREPARATION | FUJIMOTO SEIYAKU KK | 1981-05-13 | — | — | JP | disclosed |