SCHEMBL1121916

SCHEMBL1121916

CCCCCCC(C(=O)O)c1cc2c(Cl)cc(Cl)cc2[nH]1

nearest known ligand 0.45

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
GRIN1 Q05586 1/20 0.45
ALOX15 P16050 4/20 0.36
CPB2 Q96IY4 3/20 0.36
MAPT P10636 1/20 0.36
RHEB Q15382 1/20 0.36
EIF4A3 P38919 1/20 0.35
GPR84 Q9NQS5 3/20 0.35
GSK3B P49841 2/20 0.35
FFAR1 O14842 1/20 0.35
CPB1 P15086 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1122054 0.81 ALOX15 (0.51) ALOX15MAPTGPR84FFAR1
SCHEMBL1121989 0.81 CPB2 (0.35) CPB2MAPTGPR84FFAR1CPB1
SCHEMBL1121802 0.78 SIRT1 (0.35) CPB2MAPTGSK3BCPB1
SCHEMBL1121935 0.76 LCK (0.35) ALOX15CPB2MAPTGPR84GSK3B
SCHEMBL8540222 0.74 GRIN1 (0.55) GRIN1ALOX15MAPTRHEBEIF4A3
SCHEMBL1121804 0.73 DRD2 (0.46) MAPT
SCHEMBL19182733 0.73 DRD2 (0.46) MAPT
SCHEMBL10900703 0.72 MAPK1 (0.40) MAPTGPR84FFAR1
SCHEMBL1121894 0.72 GPR84 (0.34) ALOX15CPB2MAPTGPR84FFAR1
SCHEMBL12500463 0.71 MAPT (0.48) MAPTGPR84FFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9328373-B2 Detection of Salmonella lactose+ RAMBACH ALAIN (FR) 2016-05-03 US claimed
EP-1931796-B9 DETECTION OF SALMONELLA LACTOSE+ RAMBACH ALAIN (FR) 2011-06-08 EP claimed
EP-1931796-B1 DETECTION OF SALMONELLA LACTOSE+ RAMBACH ALAIN (FR) 2011-02-09 EP claimed
US-20100297690-A1 Detection of salmonella lactose+ RAMBACH ALAIN 2010-11-25 US claimed
US-9328373-B2 Detection of Salmonella lactose+ RAMBACH ALAIN (FR) 2016-05-03 US disclosed
US-20100297690-A1 Detection of salmonella lactose+ RAMBACH ALAIN 2010-11-25 US disclosed