Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | GALR2 | O43603 | 1/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | XBP1 | P17861 | 1/20 | 0.40 |
| ▸ | CCR6 | P51684 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11274736 | 0.88 | HCAR3 (0.57) | HCAR3LMNAMAPTALDH1A1NPC1 | |
| SCHEMBL11208114 | 0.88 | HCAR3 (0.47) | HCAR3LMNAMAPTALDH1A1NPC1 | |
| SCHEMBL11231775 | 0.79 | LMNA (0.42) | LMNAMAPTALDH1A1RECQLHPGD | |
| SCHEMBL11220359 | 0.79 | VCAM1 (0.43) | LMNAMAPTALDH1A1HTTL3MBTL1 | |
| Acetamide SCHEMBL17254513 | 0.77 | HCAR3 (0.54) | HCAR3LMNAMAPTALDH1A1DCTPP1 | |
| SCHEMBL13401684 | 0.77 | HCAR3 (0.64) | HCAR3LMNAMAPTALDH1A1HTT | |
| SCHEMBL11071632 | 0.74 | MAPT (0.42) | LMNAMAPTALDH1A1NPC1PKM | |
| SCHEMBL13206384 | 0.74 | LMNA (0.61) | HCAR3LMNAMAPTALDH1A1HTT | |
| SCHEMBL11267369 | 0.73 | HCAR3 (0.43) | HCAR3LMNAMAPTALDH1A1NPC1 | |
| SCHEMBL11061402 | 0.73 | ALDH1A1 (0.36) | LMNAMAPTALDH1A1HTTRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4344957-A | Benz-acyl-benzimidazole derivatives and antiallergic compositions | CIBA-GEIGY CORPORATION (US) | 1982-08-17 | — | — | US | disclosed |
| US-4213993-A | ANTIALLERGENS | CIBA-GEIGY CORPORATION (US) | 1980-07-22 | — | — | US | disclosed |
| US-4141982-A | ANTIALLERGENS | CIBA-GEIGY CORPORATION (US) | 1979-02-27 | — | — | US | disclosed |