Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 9/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | PGK1 | P00558 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11220359 | 0.88 | VCAM1 (0.43) | VCAM1ALDH1A1POLBCYP3A4PGK1 | |
| SCHEMBL11267369 | 0.84 | HCAR3 (0.43) | VCAM1ALDH1A1POLBCYP3A4HPGD | |
| SCHEMBL11758068 | 0.78 | CA12 (0.56) | VCAM1ALDH1A1CYP3A4HPGDTSHR | |
| SCHEMBL17804319 | 0.77 | L3MBTL1 (0.41) | VCAM1ALDH1A1CYP3A4HPGDALOX15 | |
| SCHEMBL2080107 | 0.77 | ALDH1A1 (0.52) | ALDH1A1POLBCYP3A4HPGDTSHR | |
| SCHEMBL11219158 | 0.77 | VCAM1 (0.64) | VCAM1ALDH1A1HPGD | |
| SCHEMBL12427042 | 0.77 | MEN1 (0.49) | VCAM1ALDH1A1CYP3A4PGK1HPGD | |
| SCHEMBL613001 | 0.76 | ALDH1A1 (0.53) | VCAM1ALDH1A1CYP3A4TSHRCA12 | |
| SCHEMBL10562304 | 0.76 | VCAM1 (0.49) | VCAM1ALDH1A1CYP3A4TSHRCA12 | |
| SCHEMBL241366 | 0.76 | VCAM1 (0.42) | VCAM1ALDH1A1CYP3A4PGK1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4344957-A | Benz-acyl-benzimidazole derivatives and antiallergic compositions | CIBA-GEIGY CORPORATION (US) | 1982-08-17 | — | — | US | disclosed |
| US-4213993-A | ANTIALLERGENS | CIBA-GEIGY CORPORATION (US) | 1980-07-22 | — | — | US | disclosed |
| US-4141982-A | ANTIALLERGENS | CIBA-GEIGY CORPORATION (US) | 1979-02-27 | — | — | US | disclosed |