Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | PPIA | P62937 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28990036 | 0.79 | TDP1 (0.56) | ALDH1A1TSHRCYP3A4HSD17B10MEN1 | |
| SCHEMBL6519433 | 0.79 | CASP6 (0.37) | ALDH1A1TSHRCYP3A4HSD17B10SMN1; SMN2 | |
| SCHEMBL3805821 | 0.79 | VCAM1 (0.54) | ALDH1A1TSHRMEN1KMT2AMAPT | |
| SCHEMBL4633629 | 0.79 | VCAM1 (0.54) | ALDH1A1TSHRMEN1KMT2AMAPT | |
| Zinc Ion SCHEMBL6519962 | 0.77 | CASP6 (0.36) | ALDH1A1TSHRCYP3A4HSD17B10SMN1; SMN2 | |
| SCHEMBL6513978 | 0.77 | CASP6 (0.36) | ALDH1A1TSHRCYP3A4HSD17B10SMN1; SMN2 | |
| SCHEMBL2726273 | 0.77 | VCAM1 (0.53) | ALDH1A1TSHRMEN1KMT2AMAPT | |
| SCHEMBL6513974 | 0.77 | CASP6 (0.36) | ALDH1A1TSHRCYP3A4HSD17B10SMN1; SMN2 | |
| SCHEMBL6519958 | 0.77 | CASP6 (0.36) | ALDH1A1TSHRCYP3A4HSD17B10SMN1; SMN2 | |
| SCHEMBL6513185 | 0.77 | TXNRD1 (0.43) | ALDH1A1MEN1KMT2AMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9499557-B2 | Transition metal-catalyzed processes for the preparation of N-allyl compounds and use thereof | RHODES TECHNOLOGIES (US) | 2016-11-22 | — | — | US | disclosed |
| US-20150353569-A1 | TRANSITION METAL-CATALYZED PROCESSES FOR THE PREPARATION OF N-ALLYL COMPOUNDS AND USE THEREOF | NORAMCO, LLC | 2015-12-10 | — | — | US | disclosed |
| US-9127014-B2 | Transition metal-catalyzed processes for the preparation of N-allyl compounds and use thereof | RHODES TECHNOLOGIES (US) | 2015-09-08 | — | — | US | disclosed |
| US-20130102780-A1 | TRANSITION METAL-CATALYZED PROCESSES FOR THE PREPARATION OF N-ALLYL COMPOUNDS AND USE THEREOF | RHODES TECHNOLOGIES (US) | 2013-04-25 | — | — | US | disclosed |
| US-4349454-A | ENCAPSULATION OF A HYDROPHOBIC-SOLVENT SOLUTION OF A DIAMINODIARYL METHANE SULFONE DERIVATIVE | KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) | 1982-09-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150353569-A1 | TRANSITION METAL-CATALYZED PROCESSES FOR THE PREPARATION OF N-ALLYL COMPOUNDS AND USE THEREOF | OPRK1, OPRM1, OPRD1 | ALDH1A1 587/4885TSHR 2404/4885CYP3A4 19/4885 |
| US-20130102780-A1 | TRANSITION METAL-CATALYZED PROCESSES FOR THE PREPARATION OF N-ALLYL COMPOUNDS AND USE THEREOF | OPRK1, OPRM1, OPRD1 | ALDH1A1 587/4885TSHR 2404/4885CYP3A4 19/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.