Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 1/20 | 0.49 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | ADAMTS5 | Q9UNA0 | 5/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.41 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.41 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.41 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.41 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.41 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.41 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.41 |
| ▸ | SPR | P35270 | 1/20 | 0.41 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.39 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11232216 | 0.89 | AVPR1A (0.51) | AVPR1AMCHR1PARP1ADAMTS5ESR1 | |
| SCHEMBL11235502 | 0.87 | AVPR1A (0.47) | AVPR1AMCHR1PARP1ADAMTS5ESR1 | |
| SCHEMBL11236498 | 0.85 | AVPR1A (0.49) | AVPR1AMCHR1PARP1ADAMTS5ESR1 | |
| SCHEMBL11354008 | 0.84 | ALDH1A1 (0.47) | AVPR1APARP1ADAMTS5ESR1SPR | |
| SCHEMBL11223947 | 0.82 | AVPR1A (0.62) | AVPR1AMCHR1PARP1ESR1PRKAB2 | |
| SCHEMBL11234418 | 0.82 | TPSAB1 (0.46) | AVPR1APARP1ADAMTS5ESR1TPSAB1 | |
| SCHEMBL11223398 | 0.81 | ADAM17 (0.57) | AVPR1APARP1ESR1TPSAB1ADAM17 | |
| SCHEMBL11244938 | 0.81 | TPSAB1 (0.55) | AVPR1APARP1ADAMTS5ESR1TPSAB1 | |
| SCHEMBL11256286 | 0.80 | ALDH1A1 (0.44) | AVPR1APARP1ADAM17 | |
| SCHEMBL11250198 | 0.78 | PARP1 (0.44) | AVPR1APARP1ADAMTS5ESR1TPSAB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0007399-B1 | INDOLYLALKYL AMINES, PHARMACEUTICAL PREPARATIONS CONTAINING THEM AND PROCESS FOR THEIR MANUFACTURE | MERCK PATENT GmbH (DE) | 1982-01-20 | — | — | EP | disclosed |
| US-4251538-A | Indolealkylamines and processes for their preparation | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1981-02-17 | — | — | US | disclosed |
| EP-0007399-A1 | Indolylalkyl amines, pharmaceutical preparations containing them and process for their manufacture | MERCK PATENT GmbH (DE) | 1980-02-06 | — | — | EP | disclosed |