SCHEMBL112297

SCHEMBL112297

COC(=O)Cc1ccc(CO)cc1

nearest known ligand 0.71

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CYP4F2 P78329 1/20 0.71
CYP4A11 Q02928 1/20 0.71
HSP90AB1 P08238 1/20 0.53
ALDH1A1 P00352 4/20 0.53
GAA P10253 1/20 0.53
GFER P55789 1/20 0.53
KMT2A Q03164 2/20 0.50
SMN1; SMN2 Q16637 5/20 0.49
NPC1 O15118 4/20 0.49
RAB9A P51151 4/20 0.49
MAPT P10636 3/20 0.49
TP53 P04637 2/20 0.49
LMNA P02545 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
KDM4E B2RXH2 1/20 0.47
HPGD P15428 1/20 0.46
HTT P42858 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4113212 0.91 CYP4F2 (0.76) CYP4F2CYP4A11HSP90AB1ALDH1A1GAA
SCHEMBL29963675 0.83 CYP4F2 (0.67) CYP4F2CYP4A11HSP90AB1ALDH1A1GAA
SCHEMBL9332759 0.83 CYP4A11 (1.00) CYP4F2CYP4A11HSP90AB1ALDH1A1GAA
SCHEMBL1107142 0.83 CYP4F2 (0.66) CYP4F2CYP4A11HSP90AB1ALDH1A1GAA
SCHEMBL112488 0.83 CYP4F2 (0.66) CYP4F2CYP4A11HSP90AB1ALDH1A1GAA
SCHEMBL7981410 0.83 CYP4F2 (0.66) CYP4F2CYP4A11HSP90AB1ALDH1A1GAA
SCHEMBL4613929 0.83 CYP4F2 (0.66) CYP4F2CYP4A11HSP90AB1ALDH1A1GAA
SCHEMBL4104271 0.83 CYP4F2 (0.66) CYP4F2CYP4A11HSP90AB1ALDH1A1GAA
SCHEMBL5546570 0.83 CYP4F2 (0.66) CYP4F2CYP4A11HSP90AB1ALDH1A1GAA
SCHEMBL28063710 0.82 CYP4F2 (0.59) CYP4F2CYP4A11HSP90AB1ALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 174 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116731677-B Foam dust settling agent for mines and preparation method thereof 燕京装备制造有限公司 2026-02-27 CN claimed
CN-116731677-A Foam dust settling agent for mines and preparation method thereof 燕京装备制造有限公司 2023-09-12 CN claimed
CN-116731677-B Foam dust settling agent for mines and preparation method thereof 燕京装备制造有限公司 2026-02-27 CN disclosed
US-12454525-B2 IL4I1 inhibitors and methods of use MERCK SHARP & DOHME LLC (US) 2025-10-28 US disclosed
US-20250127904-A1 SIGLEC LIGANDS, CONJUGATES, AND METHODS OF USE THEREOF ADAXION THERAPEUTICS, INC. 2025-04-24 US disclosed
WO-2025076427-A1 SIGLEC LIGANDS, CONJUGATES, AND METHODS OF USE THEREOF OSPREY BIOPHARMACEUTICALS, INC. (US) 2025-04-10 WO disclosed
US-20250109106-A1 Synthetic intermediates and improved processes for preparing ROCk inhibitors ALCON INC. (CH) 2025-04-03 US disclosed
EP-3845276-B1 BETA-AMINO ACID DERIVATIVE, KINASE INHIBITOR AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME, AND USE OF THE SAME IND TECH RES INST (TW) 2025-01-29 EP disclosed
US-20240383893-A1 Hydroxamic Acid Compound Having ENPP1 Inhibitory Activity and Use Thereof HAIHE BIOPHARMA CO., LTD. (CN) 2024-11-21 US disclosed
EP-4463439-A1 SYNTHETIC INTERMEDIATES AND IMPROVED PROCESSES FOR PREPARING ROCK INHIBITORS Alcon Inc. (CH) 2024-11-20 EP disclosed
EP-4400493-A1 HYDROXAMIC ACID COMPOUND HAVING ENPP1 INHIBITORY ACTIVITY AND USE THEREOF Haihe Biopharma Co., Ltd. (CN) 2024-07-17 EP disclosed
EP-0690859-A1 BENZYLIMIDAZOPYRIDINE DERIVATIVES AS ANGIOTENSIN II RECEPTOR ANTAGONISTS PFIZER INC. (US) 1996-01-10 EP disclosed
US-5395849-A Hybrid antitumor compounds containing a cyclic enediyne and a DNA-binder BRISTOL-MYERS SQUIBB COMPANY (US) 1995-03-07 US disclosed
WO-1994020499-A1 BENZYLIMIDAZOPYRIDINE DERIVATIVES AS ANGIOTENSIN II RECEPTOR ANTAGONISTS PFIZER INC. (US) 1994-09-15 WO disclosed
WO-1994020498-A1 BENZYLIMIDAZOPYRIDINE DERIVATIVE AS ANGIOTENSIN II RECEPTOR ANTAGONIST PFIZER INC. (US) 1994-09-15 WO disclosed
US-5300668-A Certain esters of 1-(4-X-methylphenyl)cyclopent-3-ene-1-carboxylic acid, wherein X is a trialkylsilyloxy, bromo or hydroxy group, as intermediates PFIZER INC. (US) 1994-04-05 US disclosed
US-5149462-A Used as ferroelectric liquid crystal MITSUBISHI RAYON COMPANY LTD. (JP) 1992-09-22 US disclosed
US-5059610-A QUINOLINE DERIVATIVES AND THEIR USE AS ANTAGONISTS OF LEUKOTRIENE D4 RHONE-POULENC RORER PHARMACEUTICALS INC. (US) 1991-10-22 US disclosed
EP-0409066-A2 Optically active compound for liquid crystal and its use MITSUBISHI RAYON COMPANY, LTD. (JP) 1991-01-23 EP disclosed
US-4920132-A Quinoline derivatives and use thereof as antagonists of leukotriene D4 RORER PHARMACEUTICAL CORP. (US) 1990-04-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250127904-A1 SIGLEC LIGANDS, CONJUGATES, AND METHODS OF USE THEREOF SIGLEC7, SIGLEC9, SELPLG CYP4F2 1606/4885CYP4A11 3099/4885HSP90AB1 3381/4885
US-20250109106-A1 Synthetic intermediates and improved processes for preparing ROCk inhibitors ROCK1, ROCK2, RHOA CYP4F2 3094/4885CYP4A11 405/4885HSP90AB1 2736/4885
US-20240383893-A1 Hydroxamic Acid Compound Having ENPP1 Inhibitory Activity and Use Thereof ENPP1, ENPP2, ENPP3 CYP4F2 4206/4885CYP4A11 3536/4885HSP90AB1 233/4885
US-12454525-B2 IL4I1 inhibitors and methods of use IL4I1, IL4, IL2 CYP4F2 243/4885CYP4A11 75/4885HSP90AB1 1778/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.