SCHEMBL11234739

SCHEMBL11234739

CNC(=O)C(C(=NO)n1cncn1)c1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
FAAH O00519 2/20 0.43
MGLL Q99685 2/20 0.43
CYP26A1 O43174 4/20 0.40
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
ALDH1A1 P00352 2/20 0.39
GAA P10253 1/20 0.39
LMNA P02545 2/20 0.38
PDE4B Q07343 1/20 0.36
CYP19A1 P11511 1/20 0.36
CYP1A2 P05177 1/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2D6 P10635 1/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35
SMN1; SMN2 Q16637 2/20 0.34
PKM P14618 1/20 0.33
MAPT P10636 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11235119 0.79 CYP26A1 (0.40) FAAHMGLLCYP26A1MEN1KMT2A
SCHEMBL11237997 0.75 MEN1 (0.33) FAAHMGLLMEN1KMT2AALDH1A1
SCHEMBL11230869 0.74 RAB9A (0.33) FAAHMGLLCYP26A1MEN1KMT2A
SCHEMBL11233549 0.69 CYP26A1 (0.31) CYP26A1LMNASMN1; SMN2PKMMAPT
SCHEMBL11241867 0.69 RAB9A (0.32) CYP26A1LMNASMN1; SMN2PKMMAPT
SCHEMBL1261044 0.68 FAAH (0.51) FAAHMGLLMEN1KMT2AALDH1A1
SCHEMBL28777621 0.68 SRC (0.64) MEN1KMT2AALDH1A1LMNACYP2D6
SCHEMBL6162357 0.66 LMNA (0.51) KMT2AALDH1A1LMNASMN1; SMN2
SCHEMBL9055207 0.66 LMNA (0.51) KMT2AALDH1A1LMNASMN1; SMN2
SCHEMBL1260790 0.65 FAAH (0.51) FAAHMGLLCYP26A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4359469-A Combating pests with N-sulphenylated oxime-carbamates BAYER AKTIENGESELLSCHAFT (DE) 1982-11-16 US disclosed