Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | SLC12A2 | P55011 | 1/20 | 0.31 |
| ▸ | SLC12A5 | Q9H2X9 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6624213 | 0.73 | PTPN1 (0.33) | MEN1KMT2APDE4BALDH1A1HSD11B1 | |
| SCHEMBL23208275 | 0.71 | MEN1 (0.41) | HTTMEN1KMT2APKMALDH1A1 | |
| SCHEMBL6618440 | 0.70 | MTNR1A (0.35) | HSD11B1 | |
| SCHEMBL6621235 | 0.70 | HSD11B1 (0.33) | HSD11B1 | |
| SCHEMBL1423618 | 0.70 | ALDH1A1 (0.37) | MEN1KMT2APDE4BALDH1A1HSD11B1 | |
| SCHEMBL23208274 | 0.70 | MEN1 (0.30) | MEN1KMT2A | |
| SCHEMBL24967885 | 0.69 | MEN1 (0.31) | MEN1KMT2APDE4BHSD11B1NPC1 | |
| SCHEMBL6624111 | 0.69 | PDE4B (0.39) | HTTTSHRPKMPDE4BALDH1A1 | |
| SCHEMBL23907104 | 0.68 | DHFR (0.37) | MEN1KMT2APDE4BHSD11B1NPC1 | |
| SCHEMBL12709562 | 0.68 | AR (0.36) | KMT2AALDH1A1GAACNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4310467-A | Process and intermediates for the synthesis of vitamin D3 metabolites | HOFFMANN-LA ROCHE INC. (US) | 1982-01-12 | — | — | US | disclosed |