Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 6/20 | 0.38 |
| ▸ | DNM2 | P50570 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.35 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17447459 | 0.69 | ALDH1A1 (0.58) | LMNASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL11665043 | 0.67 | CYP3A4 (0.39) | DNM2NPSR1S1PR2LMNASMN1; SMN2 | |
| SCHEMBL3189851 | 0.66 | TLR8 (0.40) | TLR8DNM2NPSR1S1PR2LMNA | |
| SCHEMBL11112293 | 0.66 | ELANE (0.39) | DNM2NPSR1KCNH3MAPTHTT | |
| SCHEMBL11600567 | 0.66 | DNM2 (0.44) | TLR8DNM2NPSR1S1PR2LMNA | |
| SCHEMBL11562654 | 0.66 | KCNH3 (0.42) | DNM2NPSR1S1PR2LMNASMN1; SMN2 | |
| SCHEMBL11535323 | 0.64 | ELANE (0.43) | TLR8DNM2LMNASMN1; SMN2KCNH3 | |
| SCHEMBL4612505 | 0.64 | ALDH1A1 (0.41) | LMNAMAPTALDH1A1 | |
| SCHEMBL11539500 | 0.63 | DNM2 (0.44) | TLR8DNM2NPSR1LMNASMN1; SMN2 | |
| SCHEMBL658589 | 0.63 | ALDH1A1 (0.62) | DNM2NPSR1S1PR2LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-57102875-A | — | — | None | — | — | JP | disclosed |
| JP-S57102875-A | 5-ACYLAMINO-4-METHYLOXAZOLE AND ITS PREPARATION | DAI ICHI SEIYAKU CO LTD | 1982-06-26 | — | — | JP | disclosed |