Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 4/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | MAOA | P21397 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 2/20 | 0.51 |
| ▸ | CA2 | P00918 | 2/20 | 0.51 |
| ▸ | CA9 | Q16790 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4580300 | 0.84 | ALDH1A1 (0.69) | ALDH1A1KDM4EPOLBHPGDTSHR | |
| Hydrochloric Acid SCHEMBL10348659 | 0.83 | ALDH1A1 (0.68) | ALDH1A1KDM4EPOLBHPGDTSHR | |
| SCHEMBL10336968 | 0.82 | KDM4E (0.64) | ALDH1A1KDM4EPOLBHPGDTSHR | |
| SCHEMBL11238408 | 0.79 | LMNA (0.69) | ALDH1A1KDM4EPOLBHPGDTSHR | |
| SCHEMBL10683676 | 0.78 | CA1 (0.52) | ALDH1A1KDM4EPKMPOLBHPGD | |
| SCHEMBL4579225 | 0.78 | LMNA (0.61) | ALDH1A1KDM4EPOLBHPGDTSHR | |
| SCHEMBL8356152 | 0.78 | CYP1A2 (0.68) | ALDH1A1KDM4EHPGDTSHRMAOA | |
| SCHEMBL10983258 | 0.75 | GPR27 (0.63) | ALDH1A1POLBMEN1KMT2A | |
| SCHEMBL11341388 | 0.75 | KDM4E (0.54) | ALDH1A1KDM4EHPGDTSHRMAOA | |
| SCHEMBL7320733 | 0.75 | DRD3 (0.61) | POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4334004-A | Light-sensitive diazotype material with 2-hydroxy-3-naphthoic acid amides having 6-sulfonic acid amide substitution | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-06-08 | — | — | US | claimed |
| US-4321373-A | 2-Hydroxy-3-naphthoic acid amides | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-03-23 | — | — | US | claimed |
| US-4334004-A | Light-sensitive diazotype material with 2-hydroxy-3-naphthoic acid amides having 6-sulfonic acid amide substitution | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-06-08 | — | — | US | disclosed |
| US-4321373-A | 2-Hydroxy-3-naphthoic acid amides | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-03-23 | — | — | US | disclosed |