SCHEMBL1123863

SCHEMBL1123863

C=CC(=O)Nc1ccccc1OB(O)O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TGM2 P21980 5/20 0.47
LMNA P02545 4/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
ALDH1A1 P00352 2/20 0.43
MAPT P10636 2/20 0.43
HTT P42858 2/20 0.43
GAA P10253 1/20 0.43
PTPN1 P18031 1/20 0.43
PTPN11 Q06124 1/20 0.43
MMP1 P03956 3/20 0.42
MMP2 P08253 3/20 0.42
MMP9 P14780 3/20 0.42
EGFR P00533 2/20 0.42
MAPK3 P27361 1/20 0.42
MCL1 Q07820 1/20 0.40
KMT2A Q03164 2/20 0.40
PKM P14618 1/20 0.39
NLRP1 Q9C000 1/20 0.39
MAP3K7 O43318 1/20 0.39
MAPK1 P28482 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29886478 1.00 TGM2 (0.47) TGM2LMNASMN1; SMN2ALDH1A1MAPT
SCHEMBL31242735 0.81 LMNA (0.52) LMNASMN1; SMN2ALDH1A1MAPTHTT
SCHEMBL1379751 0.80 SMN1; SMN2 (0.67) LMNASMN1; SMN2ALDH1A1MAPTHTT
SCHEMBL3182061 0.79 TGM2 (0.49) TGM2LMNASMN1; SMN2ALDH1A1MAPT
SCHEMBL31228347 0.78 TGM2 (0.65) TGM2LMNASMN1; SMN2ALDH1A1MAPT
SCHEMBL613090 0.78 TGM2 (0.65) TGM2LMNASMN1; SMN2ALDH1A1MAPT
SCHEMBL6551803 0.78 ALDH1A1 (0.56) LMNASMN1; SMN2ALDH1A1HTTKMT2A
SCHEMBL30634538 0.78 ALDH1A1 (0.56) LMNASMN1; SMN2ALDH1A1HTTKMT2A
SCHEMBL3182066 0.77 ALDH1A1 (0.47) TGM2LMNASMN1; SMN2ALDH1A1MAPT
SCHEMBL29277127 0.77 ALDH1A1 (0.50) TGM2LMNASMN1; SMN2ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024253550-A1 THE METHOD OF PREPARATION OF THE MEDICINAL FORMULATION OF CLOTRIMAZOLE WITH AMPHIPHILIC COPOLYMER AND ITS APPLICATION IN ANTICANCER THERAPY AND COMBINED ANTICANCER THERAPY WITH NIFURATEL. Centrum Badań Molekularnych i Makromolekularnych PAN (PL) 2024-12-12 WO claimed
CN-108391440-A Boric acid containing polymers for use in papermaking processes 艺康美国股份有限公司 2018-08-10 CN claimed
WO-2024253550-A1 THE METHOD OF PREPARATION OF THE MEDICINAL FORMULATION OF CLOTRIMAZOLE WITH AMPHIPHILIC COPOLYMER AND ITS APPLICATION IN ANTICANCER THERAPY AND COMBINED ANTICANCER THERAPY WITH NIFURATEL. Centrum Badań Molekularnych i Makromolekularnych PAN (PL) 2024-12-12 WO disclosed
CN-116791272-A Flame-retardant automobile interior trim panel composite material and preparation method thereof 宁波尚唯汽车饰件有限公司 2023-09-22 CN disclosed
CN-108391440-A Boric acid containing polymers for use in papermaking processes 艺康美国股份有限公司 2018-08-10 CN disclosed
CN-105380668-A Method for utilizing magneto-acoustic resonance to continuously monitor blood glucose change SUZHOU KANGCI METAL TECH CO LTD 2016-03-09 CN disclosed
CN-105277612-A Thin film composite probe for sensing measurement and preparation method thereof CAMBRIDGE ENTPR LTD 2016-01-27 CN disclosed
CN-105259249-A MAGNETIC ACOUSTIC RESONATOR SENSOR for non-invasive glucose monitoring SUZHOU QUANTZ MEDICAL TECHNOLOGY CO LTD 2016-01-20 CN disclosed
CN-102918389-B Magneto-acoustic resonant sensor Suzhou Kangxi Medical Technology Co.,Ltd. (CN) 2015-11-25 CN disclosed
CN-102918389-A Magneto-acoustic resonant sensor CAMBRIDGE ENTPR LTD 2013-02-06 CN disclosed
EP-2464740-A1 STIMULI RESPONSIVE MEMBRANE Sensile Pat AG (CH) 2012-06-20 EP disclosed
US-20120150006-A1 STIMULI RESPONSIVE MEMBRANE SENSILE PAT AG (CH) 2012-06-14 US disclosed
WO-2011018752-A1 STIMULI RESPONSIVE MEMBRANE SENSILE PAT AG (CH) 2011-02-17 WO disclosed
EP-2284275-A1 Stimuli Responsive Membrane Sensile Pat AG (CH) 2011-02-16 EP disclosed