Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 2/20 | 0.36 |
| ▸ | GSK3B | P49841 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RHEB | Q15382 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.34 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.33 |
| ▸ | AKT1 | P31749 | 1/20 | 0.33 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.33 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | BRAF | P15056 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NFATC1 | O95644 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7278230 | 0.84 | PIK3R1 (0.36) | GCGRGSK3BRAB9ANPC1MAPK1 | |
| SCHEMBL11232696 | 0.80 | CYP2C19 (0.50) | GSK3BAAK1HTT | |
| SCHEMBL11233810 | 0.78 | PDE7A (0.43) | RAB9ANPC1MAPT | |
| SCHEMBL11155642 | 0.78 | CASP1 (0.51) | MAPT | |
| SCHEMBL7278990 | 0.77 | PDE3B (0.47) | RAB9ANPC1RHEBMAPK1DUSP3 | |
| SCHEMBL11233222 | 0.76 | GSK3B (0.40) | GSK3BRAB9ANPC1MAPK1AKT1 | |
| SCHEMBL11172843 | 0.76 | RAB9A (0.37) | GCGRGSK3BRAB9ANPC1MAPK1 | |
| SCHEMBL11254135 | 0.73 | KIF11 (0.39) | GCGRRAB9ANPC1RHEBMAPK1 | |
| SCHEMBL7278975 | 0.73 | PDE3B (0.49) | GSK3BRAB9ANPC1RHEBMAPK1 | |
| SCHEMBL11389347 | 0.73 | CASP1 (0.58) | GCGRGSK3BMAPK1MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4351941-A | Pyridinyl-pyridines | STERLING DRUG INC. (US) | 1982-09-28 | — | — | US | disclosed |
| US-4331672-A | 5-(Pyridinyl)pyridine-2-hydrazines, their preparation and their cardiotonic use | STERLING DRUG INC. (US) | 1982-05-25 | — | — | US | disclosed |