Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 12/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.50 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11245895 | 0.81 | SLC6A3 (0.40) | SLC6A3SLC6A4MAPTTSHRHSD17B10 | |
| SCHEMBL654652 | 0.81 | SLC6A3 (0.40) | SLC6A3SLC6A4KMT2A | |
| SCHEMBL11244400 | 0.80 | SLC6A3 (0.39) | SLC6A3SLC6A4MAPTTSHRHSD17B10 | |
| SCHEMBL384569 | 0.75 | SLC6A3 (0.39) | SLC6A3SLC6A4TSHR | |
| SCHEMBL2286519 | 0.70 | SLC6A3 (0.56) | SLC6A3SLC6A4TSHRHSD17B10ALDH1A1 | |
| SCHEMBL6762602 | 0.70 | SLC6A3 (1.00) | SLC6A3SLC6A4 | |
| SCHEMBL15586501 | 0.69 | SLC6A3 (0.46) | SLC6A3SLC6A4TSHRHSD17B10SMN1; SMN2 | |
| SCHEMBL19807403 | 0.69 | KCNH2 (0.46) | SLC6A3SLC6A4CHRNB2CHRNA4TSHR | |
| SCHEMBL31332791 | 0.69 | SLC6A3 (0.42) | SLC6A3SLC6A4TSHR | |
| SCHEMBL27589682 | 0.69 | SLC6A3 (0.42) | SLC6A3SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4349552-A | TREATMENT OF CANCER | FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) | 1982-09-14 | — | — | US | claimed |
| EP-0010941-B1 | 5-FLUOROURACIL DERIVATIVES, PREPARATION THEREOF AND THEIR PHARMACEUTICAL COMPOSITIONS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1982-05-12 | — | — | EP | claimed |
| EP-0010941-A1 | 5-Fluorouracil derivatives, preparation thereof and their pharmaceutical compositions | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1980-05-14 | — | — | EP | claimed |