Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 6/20 | 0.34 |
| ▸ | CA1 | P00915 | 6/20 | 0.34 |
| ▸ | CA2 | P00918 | 6/20 | 0.34 |
| ▸ | CA7 | P43166 | 6/20 | 0.34 |
| ▸ | CA9 | Q16790 | 6/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 6/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.32 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11239464 | 0.81 | SLC6A3 (0.53) | SLC6A3SLC6A4ALDH1A1HSD17B10MAPT | |
| SCHEMBL654652 | 0.79 | SLC6A3 (0.40) | SLC6A3SLC6A4KDM4EALOX15MEN1 | |
| SCHEMBL11244400 | 0.77 | SLC6A3 (0.39) | SLC6A3SLC6A4ALDH1A1KDM4ELMNA | |
| SCHEMBL13516923 | 0.75 | ALDH1A1 (0.46) | SLC6A3ALDH1A1KDM4EUSP2LMNA | |
| SCHEMBL384569 | 0.72 | SLC6A3 (0.39) | SLC6A3SLC6A4TSHR | |
| SCHEMBL13516924 | 0.69 | ALDH1A1 (0.41) | SLC6A3ALDH1A1KDM4EUSP2LMNA | |
| SCHEMBL5918209 | 0.66 | CYP19A1 (0.37) | ALDH1A1KDM4EUSP2LMNAHSD17B10 | |
| SCHEMBL31296921 | 0.66 | ALDH1A1 (0.41) | ALDH1A1KDM4EUSP2LMNAHSD17B10 | |
| SCHEMBL28243948 | 0.64 | ALDH1A1 (0.40) | SLC6A3ALDH1A1KDM4EUSP2LMNA | |
| SCHEMBL20443748 | 0.64 | CA12 (0.59) | ALDH1A1LMNAMAPTCA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4349552-A | TREATMENT OF CANCER | FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) | 1982-09-14 | — | — | US | claimed |
| EP-0010941-B1 | 5-FLUOROURACIL DERIVATIVES, PREPARATION THEREOF AND THEIR PHARMACEUTICAL COMPOSITIONS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1982-05-12 | — | — | EP | claimed |
| EP-0010941-A1 | 5-Fluorouracil derivatives, preparation thereof and their pharmaceutical compositions | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1980-05-14 | — | — | EP | claimed |