Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WNT3A | P56704 | 3/20 | 0.45 |
| ▸ | LRRK2 | Q5S007 | 5/20 | 0.40 |
| ▸ | MTOR | P42345 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11229323 | 0.82 | CYP1A2 (0.46) | WNT3ALRRK2MTORCYP3A4AAK1 | |
| SCHEMBL11247880 | 0.78 | ALDH1A1 (0.45) | CYP3A4 | |
| SCHEMBL11234214 | 0.72 | MTOR (0.41) | WNT3AMTOR | |
| SCHEMBL11251403 | 0.71 | PDE3B (0.50) | — | |
| SCHEMBL7270939 | 0.71 | MTOR (0.45) | MTOR | |
| SCHEMBL7273135 | 0.70 | MTOR (0.42) | MTORAAK1 | |
| SCHEMBL11223772 | 0.69 | PDE3A (0.73) | WNT3ALRRK2CYP3A4AAK1 | |
| SCHEMBL11069334 | 0.69 | MTOR (0.55) | MTOR | |
| SCHEMBL11230737 | 0.68 | MTOR (0.40) | MTORAAK1 | |
| SCHEMBL24767209 | 0.67 | WNT3A (0.48) | WNT3ALRRK2CYP3A4AAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4362734-A | 2-(Substituted-amino)-5-(pyridinyl-nicotinonitriles, and their cardiotonic use | STERLING DRUG INC. (US) | 1982-12-07 | — | — | US | disclosed |