Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 5/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.48 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | IRAK4 | Q9NWZ3 | 4/20 | 0.46 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.46 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.46 |
| ▸ | GBA1 | P04062 | 1/20 | 0.45 |
| ▸ | KRAS | P01116 | 2/20 | 0.44 |
| ▸ | GALR3 | O60755 | 1/20 | 0.44 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 3/20 | 0.44 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11256846 | 0.86 | NR2F2 (0.59) | HTTMAPK1LMNASMN1; SMN2MAPT | |
| SCHEMBL11250025 | 0.85 | NPC1 (0.52) | HTTMAPK1SMN1; SMN2MAPTGBA1 | |
| SCHEMBL11240075 | 0.84 | EGFR (0.53) | HTTMAPK1LMNASMN1; SMN2MAPT | |
| SCHEMBL11255628 | 0.79 | GBA1 (0.56) | HTTMAPK1LMNASMN1; SMN2MAPT | |
| SCHEMBL11250079 | 0.78 | PIK3CD (0.73) | HTTKDM4EMAPK1NCOA1NCOA3 | |
| SCHEMBL14595323 | 0.77 | HTT (0.71) | HTTKDM4EMAPK1NCOA1NCOA3 | |
| SCHEMBL11249399 | 0.77 | LMNA (0.75) | HTTKDM4EMAPK1NCOA1NCOA3 | |
| SCHEMBL11248882 | 0.77 | EGFR (0.52) | HTTKDM4ESMN1; SMN2MAPTPIK3CD | |
| SCHEMBL11261278 | 0.76 | EGFR (0.52) | HTTMAPK1LMNASMN1; SMN2MAPT | |
| SCHEMBL11246634 | 0.76 | SMN1; SMN2 (0.51) | HTTMAPK1LMNASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4323680-A | 4-Aminoquinazoline compounds useful as agricultural fungicides | SANKYO COMPANY LIMITED (JP) | 1982-04-06 | — | — | US | disclosed |
| US-4213987-A | 4-AMINOQUINAZOLINES | SANKYO COMPANY LIMITED (JP) | 1980-07-22 | — | — | US | disclosed |